Successful cloning of monkeys, the first non-human primate species, by somatic cell nuclear
transfer (SCNT) attracted worldwide attention earlier this year. Remarkably, it has taken …

Deer antler is the only mammalian organ that can fully grow back once lost from its pedicle–
the base from which it grows. Therefore, antlers probably offer the most pertinent model for …

Deer antlers are extraordinary mammalian organs that can fully regenerate annually. Antler
renewal is a stem cell-based epimorphic process and antler stem (AS) cells can initiate de …

Somatic cell nuclear transfer (SCNT) has broad applications but is limited by low cloning
efficiency. In this review, we mainly focus on SCNT-mediated epigenetic reprogramming in …

Mammalian organ regeneration is the “Holy Grail” of modern regenerative biology and
medicine. The most dramatic organ replacement is known as epimorphic regeneration. To …

Epigenetic aberrancies likely preclude correct and complete nuclear reprogramming
following somatic cell nuclear transfer (SCNT), and may underlie the observed reduced …

The effectiveness of somatic cell nuclear transfer (SCNT) in mammals seems to be still
characterized by the disappointingly low rates of cloned embryos, fetuses, and progeny …

It has now been 13 years since the first cloned mammal Dolly the sheep was generated from
somatic cells using nuclear transfer (SCNT). Since then, this technique has been considered …

Deer antlers are periodically replaced cranial appendages that develop from permanent
outgrowths of the frontal bones known as pedicles. Antler re-growth is a unique regenerative …

Antlers are the only fully regenerable mammalian appendages whose annual renewal is
initiated by antler stem cells (ASCs), defined as a specialized type of mesenchymal stem …