A large number of clinical trials have shown stem cell therapy to be a promising therapeutic
approach for the treatment of cardiovascular diseases. Since the first transplantation into …

The morbidity rate of myocardial ischemia and reperfusion has increased in modern society,
and oxidative stress plays a critical role in the pathological process. Nuclear factor E2 …

Despite significant therapeutic advances, the prognosis of patients with heart failure (HF)
remains poor, and current therapeutic approaches are palliative in the sense that they do not …

Understanding the processes governing the ability of the heart to repair and regenerate after
injury is crucial for developing translational medical solutions. New avenues of exploration …

In this review we examine the effects of both over-and under-production of heme oxygenase-
1 (HO-1) and HO activity on a broad spectrum of biological systems and on vascular …

Heart failure (HF) is frequently the consequence of sustained, abnormal neurohormonal,
and mechanical stress and remains a leading cause of death worldwide. The key …

Cell therapy is emerging as a viable therapy to restore neurological function after stroke.
Many types of stem/progenitor cells from different sources have been explored for their …

Stem cell transplantation therapy has emerged as a promising regenerative medicine for
ischemic stroke and other neurodegenerative disorders. However, many issues and …

The nuclear factor erythroid derived 2-related factor 2 (Nrf2) and the antioxidant protein
heme oxygenase-1 (HO-1) are crucial components of the cellular stress response. These …

The global epidemic of obesity continues unabated with sequelae of diabetes and metabolic
syndrome. This review reflects the dramatic increase in research on the role of increased …