The clinical impact of infections due to extended-spectrum β-lactamase (ESBL)-and/or
carbapenemase-producing Enterobacterales (Ent) has reached dramatic levels worldwide …

Carbapenem-resistant Enterobacterales (CRE) remain a significant public health threat,
and, despite recent approvals, new antibiotics are needed. Severe infections caused by …

The global burden of bacterial resistance remains one of the most serious public health
concerns. Infections caused by multidrug-resistant (MDR) bacteria in critically ill patients …

Infections caused by Gram-negative bacteria still pose a clinical challenge. Although
nanomaterials have been developed for antibacterial treatments, a systematic evaluation of …

Colistin, the last resort for multidrug and extensively drug-resistant bacterial infection
treatment, was reintroduced after being avoided in clinical settings from the 1970s to the …

Purpose Studies on the epidemiology of bloodstream infection (BSI) and antimicrobial
resistance (AMR) are limited in Vietnam. Thus, the present study aimed to elucidate the …

For the past few years, microbial biofilms have been emerging as a significant threat to the
modern healthcare system, and their prevalence and antibiotic resistance threat gradually …

Background Aztreonam/avibactam is under development to treat infections caused by Gram-
negative bacteria. We evaluated the in vitro activities of aztreonam/avibactam and …

The development of efficient point-of-care (POC) diagnostic tools for detecting infectious
diseases caused by destructive pathogens plays an important role in clinical and …

Pseudomonas aeruginosa is a high-priority bacterial agent that causes healthcare-acquired
infections (HAIs), which often leads to serious infections and poor prognosis in vulnerable …