[HTML][HTML] Clinical Implications of Proton Pump Inhibitors and Vonoprazan Micro/Nano Drug Delivery Systems for Gastric Acid-Related Disorders and Imaging

A Setia, RR Challa, B Vallamkonda… - …, 2024 - pmc.ncbi.nlm.nih.gov
Excessive stomach acid or bacterial infection are the root causes of gastric acid-related
disorders, such as peptic ulcer disease and gastroesophageal reflux disease. Proton pump …

Response surface methodology (RSM) powered formulation development, optimization and evaluation of thiolated based mucoadhesive nanocrystals for local …

RB Bakhaidar, NR Naveen, P Basim, SS Murshid… - Polymers, 2022 - mdpi.com
In oral administration systems, mucoadhesive polymers are crucial for drug localization and
target-specific activities. The current work focuses on the application of thiolated xanthan …

Assessment of Binary Agarose–Carbopol Buccal Gels for Mucoadhesive Drug Delivery: Ex Vivo and In Vivo Characterization

MA Syed, S Hanif, N Ain, HK Syed, AF Zahoor, IU Khan… - Molecules, 2022 - mdpi.com
Agarose (AG) is a naturally occurring biocompatible marine seaweed extract that is
converted to hydrocolloid gel in hot water with notable gel strength. Currently, its …

Development of thiolated xanthan gum-stearylamine conjugate based mucoadhesive system for the delivery of biochanin-A to melanoma cells

M Jadav, R Solanki, S Patel, D Pooja… - International Journal of …, 2024 - Elsevier
Recently, instead of creating new active compounds, scientists have been working to
increase the bioavailability and residence time of existing drugs by modifying the …

Design and evaluation of magnetic-targeted bilosomal gel for rheumatoid arthritis: flurbiprofen delivery using superparamagnetic iron oxide nanoparticles

RY Mushtaq, NR Naveen, KJ Rolla… - Frontiers in …, 2024 - frontiersin.org
Introduction The study aimed to systematically enhance the fabrication process of
flurbiprofen-loaded bilosomes (FSB) using Quality by Design (QbD) principles and Design of …

[HTML][HTML] Mannosylated preactivated hyaluronic acid-based nanostructures for bacterial infection treatment

R Arshad, MS Arshad, A Malik, M Alkholief… - International Journal of …, 2023 - Elsevier
Salmonella Typhi is an intracellular bacterium causing a variety of enteric diseases, being
typhoid fever the most common. Current modalities for treating S. typhi infection are …

Enhancement of antifungal activity and transdermal delivery of 5-flucytosine via tailored spanlastic nanovesicles: statistical optimization, in-vitro characterization, and …

AY Safhi, NR Naveen, KJ Rolla, PD Bhavani… - Frontiers in …, 2023 - frontiersin.org
Aim and background: This current study aimed to load 5-flucytosine (5-FCY) into spanlastic
nanovesicles (SPLNs) to make the drug more efficient as an antifungal and also to load the …

Design and biological evaluation of Repaglinide loaded polymeric nanocarriers for diabetes linked neurodegenerative disorder: QbD-driven optimization, in situ, in …

G Wadhwa, KV Krishna, SK Dubey, R Taliyan - International Journal of …, 2023 - Elsevier
Diabetes mellitus is a metabolic disorder characterized by inadequate insulin secretion and
signaling dysfunction, leading to a vast spectrum of systemic complications. These …

[HTML][HTML] Design and in vitro effectiveness evaluation of Echium amoenum extract loaded in bioadhesive phospholipid vesicles tailored for mucosal delivery

M Firoznezhad, R Abi-Rached, F Fulgheri… - International Journal of …, 2023 - Elsevier
Abstract The Echium amoenum Fisch. and CA Mey.(E. amoenum) is an herb native from
Iranian shrub, and its blue-violet flowers are traditionally used as medical plants. In the …

QbD Assisted Optimization of Microwave-assisted Synthesis of Polyacrylamide Grafted Tragacanth: Characterization and Instrumental Analysis

M Namballa, A Adimulapu… - Current Microwave …, 2024 - ingentaconnect.com
Background: Polysaccharides have recently attracted a lot of attention in the designing of
drug delivery systems due to their wide availability, lack of toxicity, and numerous ways that …