[HTML][HTML] Cytoskeletal remodeling in cancer

J Aseervatham - Biology, 2020 - mdpi.com
Simple Summary Cell migration is an essential process from embryogenesis to cell death.
This is tightly regulated by numerous proteins that help in proper functioning of the cell. In …

[HTML][HTML] Functional and clinical characteristics of focal adhesion kinases in cancer progression

Z Zhang, J Li, S Jiao, G Han, J Zhu… - Frontiers in Cell and …, 2022 - frontiersin.org
Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase and an adaptor protein that
primarily regulates adhesion signaling and cell migration. FAK promotes cell survival in …

[PDF][PDF] Lusutrombopag for the treatment of thrombocytopenia in patients with chronic liver disease undergoing invasive procedures (L‐PLUS 2)

M Peck‐Radosavljevic, K Simon, A Iacobellis… - …, 2019 - Wiley Online Library
Thrombocytopenia may be associated with increased bleeding risk impacting timing and
outcome of invasive procedures in patients with chronic liver disease (CLD) …

Ru nanoparticles supported on partially reduced TiO2 as highly efficient catalyst for hydrogen evolution

LN Chen, SH Wang, PY Zhang, ZX Chen, X Lin… - Nano Energy, 2021 - Elsevier
The development of low-cost yet highly efficient catalysts for hydrogen evolution reaction
(HER) is crucial for large-scale clean and sustainable hydrogen production from water …

[HTML][HTML] YAP/TAZ in bone and cartilage biology

M Zarka, E Haÿ, M Cohen-Solal - Frontiers in Cell and Developmental …, 2022 - frontiersin.org
YAP and TAZ were initially described as the main regulators of organ growth during
development and more recently implicated in bone biology. YAP and TAZ are regulated by …

TAZ target gene ITGAV regulates invasion and feeds back positively on YAP and TAZ in liver cancer cells

SME Weiler, T Lutz, M Bissinger, C Sticht, M Knaub… - Cancer Letters, 2020 - Elsevier
The Hippo pathway effectors yes-associated protein (YAP) and WW domain containing
transcription regulator 1 (TAZ/WWTR1) support tumor initiation and progression in various …

[PDF][PDF] p300 Acetyltransferase Is a Cytoplasm‐to‐Nucleus Shuttle for SMAD2/3 and TAZ Nuclear Transport in Transforming Growth Factor β–Stimulated Hepatic …

Y Wang, K Tu, D Liu, L Guo, Y Chen, Q Li… - …, 2019 - Wiley Online Library
Nuclear translocation of mothers against decapentaplegic homolog 2/3 (SMAD2/3), core
transcription factors of transforming growth factor β (TGF‐β) signaling, is critical for hepatic …

[HTML][HTML] YAP promotes VEGFA expression and tumor angiogenesis though Gli2 in human renal cell carcinoma

S Xu, H Zhang, Y Chong, B Guan, P Guo - Archives of Medical Research, 2019 - Elsevier
Background High vascularization is a major characteristic of renal cell carcinoma (RCC).
Thus, exploration of molecules promoting the tumor vascularization in RCC is urgent. Yes …

Interaction between laminin-5γ2 and integrin β1 promotes the tumor budding of colorectal cancer via the activation of Yes-associated proteins

B Zhou, S Zong, W Zhong, Y Tian, L Wang, Q Zhang… - Oncogene, 2020 - nature.com
Colorectal cancer (CRC) is a common cancer type and a threat to human health. Tumor
budding (TB) is the presence of a single cancer cell or clusters of up to five cancer cells prior …

[HTML][HTML] Association between inflammation and function of cell adhesion molecules influence on gastrointestinal cancer development

HW Huang, CC Chang, CS Wang, KH Lin - Cells, 2021 - mdpi.com
Gastrointestinal cancer is highly associated with inflammatory processes inducing the
release of cytokines from cancer or immune cells, including interferons, interleukins …