Osteoarthritis (OA) is a common musculoskeletal disease that leads to deterioration of
articular cartilage, joint pain, and decreased quality of life. When OA develops after a joint …

Tissue-level mechanics (eg, stress and strain) are important factors governing tissue
remodeling and development of knee osteoarthritis (KOA), and hence, the success of …

Traumatic joint injuries are common, leading to progressive tissue degeneration and the
development of osteoarthritis. The post-traumatic joint experiences a pro-inflammatory …

In this study, we mapped and quantified changes of proteoglycan (PG) content and
biomechanical properties in articular cartilage in which either blunt or sharp grooves had …

Background and Objectives: Tunnel enlargement (TE) is a widely reported phenomenon
after anterior cruciate ligament reconstruction (ACLR). Given the paucity of knowledge in the …

Background: Adolescents who experience a patellar dislocation have an elevated risk of
patellofemoral posttraumatic osteoarthritis. Magnetic resonance imaging (MRI)–based T1ρ …

Obesity is a known risk factor for development of osteoarthritis (OA). Numerical tools like
finite‐element (FE) models combined with degenerative algorithms have been developed to …

Gait modification is a common nonsurgical approach to alter the mediolateral distribution of
knee contact forces, intending to decelerate or postpone the progression of mechanically …

In order to improve the ability of clinical diagnosis to differentiate articular cartilage (AC)
injury of different origins, this study explores the sensitivity of mid-infrared (MIR) …

The ability of articular cartilage to withstand significant mechanical stresses during activities,
such as walking or running, relies on its distinctive structure. Integrating detailed tissue …