[HTML][HTML] Exosomes: Small vesicles with big roles in cancer, vaccine development, and therapeutics

A Thakur, DC Parra, P Motallebnejad, M Brocchi… - Bioactive materials, 2022 - Elsevier
Cancer is a deadly disease that is globally and consistently one of the leading causes of
mortality every year. Despite the availability of chemotherapy, radiotherapy, immunotherapy …

Liquid biopsies to occult brain metastasis

AU Rehman, P Khan, SK Maurya, JA Siddiqui… - Molecular cancer, 2022 - Springer
Brain metastasis (BrM) is a major problem associated with cancer-related mortality, and
currently, no specific biomarkers are available in clinical settings for early detection. Liquid …

MicroRNAs: emerging driver of cancer perineural invasion

M Zhang, H Xian, L Dai, Y Tang, X Liang - Cell & Bioscience, 2021 - Springer
The perineural invasion (PNI), which refers to tumor cells encroaching on nerve, is a clinical
feature frequently occurred in various malignant tumors, and responsible for postoperative …

Decoding molecular programs in melanoma brain metastases

J Radke, E Schumann, J Onken, R Koll, G Acker… - Nature …, 2022 - nature.com
Melanoma brain metastases (MBM) variably respond to therapeutic interventions; thus
determining patient's prognosis. However, the mechanisms that govern therapy response …

Opportunities offered by graphene nanoparticles for micrornas delivery for amyotrophic lateral sclerosis treatment

B Niccolini, V Palmieri, M De Spirito, M Papi - Materials, 2021 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is characterized by the degeneration and death of motor
neurons. This neurodegenerative disease leads to muscle atrophy, paralysis, and death due …

Plant-derived extracellular nanovesicles: a promising biomedical approach for effective targeting of triple negative breast cancer cells

L Cui, G Perini, A Augello, V Palmieri… - … in Bioengineering and …, 2024 - frontiersin.org
Introduction: Triple negative breast cancer (TNBC), a highly aggressive subtype accounting
for 15–20% of all breast cancer cases, faces limited treatment options often accompanied by …

miRNome and Proteome Profiling of Small Extracellular Vesicles Secreted by Human Glioblastoma Cell Lines and Primary Cancer Stem Cells

I Cifola, F Fratini, B Cardinali, V Palmieri, G Gatti… - Biomedicines, 2022 - mdpi.com
Glioblastoma (GBM) is the most common and aggressive brain tumor in adults. Despite
available therapeutic interventions, it is very difficult to treat, and a cure is not yet available …

Distinct mRNAs in Cancer Extracellular Vesicles Activate Angiogenesis and Alter Transcriptome of Vascular Endothelial Cells

P Zhang, SB Lim, K Jiang, TW Chew, BC Low, CT Lim - Cancers, 2021 - mdpi.com
Simple Summary Cancer extracellular vesicles (EVs) are implicated in various processes of
cancer development, with most of the EV-induced changes attributed to EV proteins and …

Modulating effects of cancer-derived exosomal miRNAs and exosomal processing by natural products

YT Chuang, JY Tang, JP Shiau, CY Yen, FR Chang… - Cancers, 2023 - mdpi.com
Simple Summary Cancer cells generate exosomes (extracellular vesicles) to regulate many
cell functions for tumor progression. Many exosome-modulating clinical drugs have been …

[PDF][PDF] 神经肌肉关节促进训练对脑性瘫痪患儿智力及肢体功能的影响

王淑慧, 高雪婷, 周银月, 肖琳, 刘婷婷 - 现代生物医学进展, 2021 - biomed.cnjournals.com
摘要目的: 探讨神经肌肉关节促进训练对脑性瘫痪(cerebral palsy, CP, 脑瘫)
患儿智力及肢体功能的影响. 方法: 2016 年12 月到2018 年12 月选择在本院儿保科门诊就诊的 …