Reactive oxygen species scavenging nanomedicine for the treatment of ischemic heart disease

Z Zhang, R Dalan, Z Hu, JW Wang… - Advanced …, 2022 - Wiley Online Library
Ischemic heart disease (IHD) is the leading cause of disability and mortality worldwide.
Reactive oxygen species (ROS) have been shown to play key roles in the progression of …

Berberine: a review of its pharmacokinetics properties and therapeutic potentials in diverse vascular diseases

X Ai, P Yu, L Peng, L Luo, J Liu, S Li, X Lai… - Frontiers in …, 2021 - frontiersin.org
Traditional Chinese medicine plays a significant role in the treatment of various diseases
and has attracted increasing attention for clinical applications. Vascular diseases affecting …

Post-myocardial infarction fibrosis: Pathophysiology, examination, and intervention

X Yin, X Yin, X Pan, J Zhang, X Fan, J Li… - Frontiers in …, 2023 - frontiersin.org
Cardiac fibrosis plays an indispensable role in cardiac tissue homeostasis and repair after
myocardial infarction (MI). The cardiac fibroblast-to-myofibroblast differentiation and …

Injectable liposomal docosahexaenoic acid alleviates atherosclerosis progression and enhances plaque stability

SY Chong, X Wang, L van Bloois… - … Clinics and Research, 2023 - journals.lww.com
Atherosclerosis is a chronic inflammatory vascular disease that is characterized by the
accumulation of lipids and immune cells in plaques built up inside artery walls …

Cell-derived nanovesicles from mesenchymal stem cells as extracellular vesicle-mimetics in wound healing

YR Neupane, HK Handral, SA Alkaff, WH Chng… - … Pharmaceutica Sinica B, 2023 - Elsevier
Wound healing is a dynamic process that involves a series of molecular and cellular events
aimed at replacing devitalized and missing cellular components and/or tissue layers …

Protection against doxorubicin-induced cardiotoxicity by ergothioneine

IK Cheah, RMY Tang, X Wang, K Sachaphibulkij… - Antioxidants, 2023 - mdpi.com
Background: Anthracyclines such as doxorubicin remain a primary treatment for
hematological malignancies and breast cancers. However, cardiotoxicity induced by …

Nanomedicine‐based therapeutics for myocardial ischemic/reperfusion injury

X Li, W Ou, M Xie, J Yang, Q Li… - Advanced Healthcare …, 2023 - Wiley Online Library
Myocardial ischemic/reperfusion (IR) injury is a global cardiovascular disease with high
mortality and morbidity. Therapeutic interventions for myocardial ischemia involve restoring …

Active factor XI is associated with the risk of cardiovascular events in stable coronary artery disease patients

E Paszek, E Pociask, M Ząbczyk, A Piórkowski… - Atherosclerosis, 2022 - Elsevier
Background and aims Tissue factor (TF) and activated factor XI (FXIa) have been associated
with acute coronary syndrome, ischemic stroke and venous thromboembolism. Their …

Myocardial delivery of miR30d with peptide-functionalized milk-derived extracellular vesicles for targeted treatment of hypertrophic heart failure

L Tong, Q Wang, Y Zhang, F Lai, J Xu, W Yin, S Zhang… - Biomaterials, 2025 - Elsevier
Abstract miR30d has been shown to reverse cardiac hypertrophy. However, effective
delivery of miR30d to the heart is challenging. Here, we engineered milk-derived …

Mechanisms and Therapeutic Strategies for Myocardial Ischemia-Reperfusion Injury in Diabetic States

J Xue, J Zhuang, X Wang, T Meng, J Wu… - ACS Pharmacology & …, 2024 - ACS Publications
In patients with myocardial infarction, one of the complications that may occur after
revascularization is myocardial ischemia-reperfusion injury (IRI), characterized by a …