Advances and perspectives in dental pulp stem cell based neuroregeneration therapies

J Luzuriaga, Y Polo, O Pastor-Alonso… - International journal of …, 2021 - mdpi.com
Human dental pulp stem cells (hDPSCs) are some of the most promising stem cell types for
regenerative therapies given their ability to grow in the absence of serum and their realistic …

Biology and pathophysiology of symptomatic neuromas

CD Hwang, YAJ Hoftiezer, FV Raasveld… - Pain, 2024 - journals.lww.com
Neuromas are a substantial cause of morbidity and reduction in quality of life. This is not
only caused by a disruption in motor and sensory function from the underlying nerve injury …

Exposure to childhood maltreatment is associated with specific epigenetic patterns in sperm

JJ Tuulari, M Bourgery, J Iversen, TG Koefoed… - Molecular …, 2025 - nature.com
Childhood maltreatment exposure (CME) increases the risk of adverse long-term health
consequences for the exposed individual. Animal studies suggest that CME may also …

Time to go: neural crest cell epithelial-to-mesenchymal transition

TA Leathers, CD Rogers - Development, 2022 - journals.biologists.com
Neural crest cells (NCCs) are a dynamic, multipotent, vertebrate-specific population of
embryonic stem cells. These ectodermally-derived cells contribute to diverse tissue types in …

Human pluripotent stem cell-derived inner ear organoids recapitulate otic development in vitro

D Doda, S Alonso Jimenez, H Rehrauer… - …, 2023 - journals.biologists.com
Our molecular understanding of the early stages of human inner ear development has been
limited by the difficulty in accessing fetal samples at early gestational stages. As an …

How to differentiate induced pluripotent stem cells into sensory neurons for disease modelling: a functional assessment

AK Kalia, C Rösseler, R Granja-Vazquez… - Stem Cell Research & …, 2024 - Springer
Background Human induced pluripotent stem cell (iPSC)-derived peripheral sensory
neurons present a valuable tool to model human diseases and are a source for applications …

Gingival mesenchymal stem cell therapy, immune cells, and immunoinflammatory application

AE Tolouei, F Oruji, S Tehrani, S Rezaei… - Molecular Biology …, 2023 - Springer
MSC-based therapeutic strategies have proven to be incredibly effective. Robust self-
renewal, multilineage differentiation, and potential for tissue regeneration and disease …

Neural crest and sons: role of neural crest cells and Schwann cell precursors in development and gland embryogenesis

A Knyazeva, V Dyachuk - Frontiers in Cell and Developmental Biology, 2024 - frontiersin.org
In this review, we consider the multipotency of neural crest cells (NCCs), Schwann cell
precursors (SCPs), and their role in embryogenesis base on genetic tracing and knock out …

Introducing dorsoventral patterning in adult regenerating lizard tails with gene-edited embryonic neural stem cells

TP Lozito, R Londono, AX Sun, ML Hudnall - Nature Communications, 2021 - nature.com
Lizards regenerate amputated tails but fail to recapitulate the dorsoventral patterning
achieved during embryonic development. Regenerated lizard tails form ependymal tubes …

gldc Is Essential for Renal Progenitor Patterning during Kidney Development

NE Weaver, A Healy, RA Wingert - Biomedicines, 2022 - mdpi.com
The glycine cleavage system (GCS) is a complex located on the mitochondrial membrane
that is responsible for regulating glycine levels and contributing one-carbon units to folate …