Deep learning tools to accelerate antibiotic discovery
Introduction As machine learning (ML) and artificial intelligence (AI) expand to many
segments of our society, they are increasingly being used for drug discovery. Recent deep …
segments of our society, they are increasingly being used for drug discovery. Recent deep …
Oral delivery of biomacromolecules by overcoming biological barriers in the gastrointestinal tract: an update
S Liu, X Wen, X Zhang, S Mao - Expert opinion on drug delivery, 2023 - Taylor & Francis
Introduction Biomacromolecules have proven to be an attractive choice for treating diseases
due to their properties of strong specificity, high efficiency, and low toxicity. Besides greatly …
due to their properties of strong specificity, high efficiency, and low toxicity. Besides greatly …
[HTML][HTML] The role of artificial intelligence in generating original scientific research
Artificial intelligence (AI) is a revolutionary technology that is finding wide application across
numerous sectors. Large language models (LLMs) are an emerging subset technology of AI …
numerous sectors. Large language models (LLMs) are an emerging subset technology of AI …
Artificial intelligence generates novel 3D printing formulations
Abstract Formulation development is a critical step in the development of medicines. The
process requires human creativity, ingenuity and in-depth knowledge of formulation …
process requires human creativity, ingenuity and in-depth knowledge of formulation …
Machine learning for antimicrobial peptide identification and design
Artificial intelligence (AI) and machine learning (ML) models are being deployed in many
domains of society and have recently reached the field of drug discovery. Given the …
domains of society and have recently reached the field of drug discovery. Given the …
[HTML][HTML] Solidification and oral delivery of biologics to the colon-a review
KT Kopp, L Saerens, J Voorspoels… - European Journal of …, 2023 - Elsevier
The oral delivery of biologics such as therapeutic proteins, peptides and oligonucleotides for
the treatment of colon related diseases has been the focus of increasing attention over the …
the treatment of colon related diseases has been the focus of increasing attention over the …
Deep learning for advancing peptide drug development: Tools and methods in structure prediction and design
X Wu, H Lin, R Bai, H Duan - European Journal of Medicinal Chemistry, 2024 - Elsevier
Peptides can bind challenging disease targets with high affinity and specificity, offering
enormous opportunities for addressing unmet medical needs. However, peptides' unique …
enormous opportunities for addressing unmet medical needs. However, peptides' unique …
Impact of Peptide Structure on Colonic Stability and Tissue Permeability
F Taherali, N Chouhan, F Wang, S Lavielle, M Baran… - Pharmaceutics, 2023 - mdpi.com
Most marketed peptide drugs are administered parenterally due to their inherent
gastrointestinal (GI) instability and poor permeability across the GI epithelium. Several …
gastrointestinal (GI) instability and poor permeability across the GI epithelium. Several …
Colon Drug Delivery Systems Based on Swellable and Microbially Degradable High-Methoxyl Pectin: Coating Process and In Vitro Performance
S Moutaharrik, L Palugan, M Cerea, G Meroni… - Pharmaceutics, 2024 - mdpi.com
Oral colon delivery systems based on a dual targeting strategy, harnessing time-and
microbiota-dependent release mechanisms, were designed in the form of a drug-containing …
microbiota-dependent release mechanisms, were designed in the form of a drug-containing …
AI-Driven Decision-Making Applications in Pharmaceutical Sciences
B Yingngam, A Navabhatra… - Using Traditional Design …, 2024 - igi-global.com
This chapter explores AI's influence on pharmaceutical sciences, highlighting its
enhancement of traditional design methodologies. It explores AI's transformational role in …
enhancement of traditional design methodologies. It explores AI's transformational role in …