Neonatal encephalopathy is a syndrome characterised by abnormal neurological function
often caused by a hypoxic insult during childbirth. Triggers such as hypoxia-ischaemia result …

Perinatal inflammation is a significant risk factor for lifelong neurodevelopmental
impairments such as cerebral palsy. Extensive clinical and preclinical evidence links the …

Hypoxic‐ischemic encephalopathy (HIE) mainly affects preterm and term newborns, leading
to a high risk of brain damage. Coexisting infection/inflammation and birth asphyxia are key …

Background Outcome in severe acute necrotizing encephalopathy of childhood is poor, with
high mortality (30%) and moderate to severe disability in survivors despite the use of …

Background Increased systemic and tissue levels of interleukin (IL)-1β are associated with
greater risk of impaired neurodevelopment after birth. In this study, we tested the hypothesis …

Neuroinflammation is a hallmark of hypoxic-ischemic injury and can be characterized by the
activation of glial cells and the expression of inflammatory cytokines and chemokines …

Monocyte-derived fibrocytes recently garnered attention because the novel pathogenesis of
myelofibrosis (MF), and suppression of fibrocyte differentiation by serum amyloid P …

Perforin plays an important role in autoimmune and infectious diseases, but its function in
immune inflammatory responses after spinal cord injury (SCI) has received insufficient …

We enumerated conventional and innate lymphocyte populations in neonates with neonatal
encephalopathy (NE), school-age children post-NE, children with cerebral palsy and age …

Background: Neonatal encephalopathy (NE) is associated with adverse
neurodevelopmental outcome and is linked with systemic inflammation. Pro-inflammatory …