Highlights•We summarize and update the germinal center model of Epstein–Barr virus
persistence.•We discuss the weaknesses and strengths of alternate models.•The role of …

We present a new approach to the study of the immune system that combines techniques of
systems biology with information provided by data-driven prediction methods. To this end …

Background. University students were studied prospectively to determine the incidence of
and risk factors for acquisition of primary Epstein–Barr virus (EBV) infection and the virologic …

The immune system is able to respond more vigorously to the second contact with a given
antigen than to the first contact. Vaccination protocols generally include at least two doses …

Background Immune system conditions of the patient is a key factor in COVID-19 infection
survival. A growing number of studies have focused on immunological determinants to …

The emergence of antibiotic-resistant microorganisms is a significant concern in global
health. Antibiotic resistance is attributed to various virulent factors and genetic elements …

The really interesting thing about herpesviruses is that they can establish lifelong persistant
infections in immunocompetent hosts. At first glance, they would seem to have very different …

Amyotrophic lateral sclerosis (ALS) is the most prevalent motor neuron disorder worldwide.
In ALS, progressing disease can result from misfolding and aggregation of superoxide …

Agent-based modeling and simulation is a useful method to study biological phenomena in
a wide range of fields, from molecular biology to ecology. Since there is currently no agreed …

Background Tuberculosis (TB) represents a worldwide cause of mortality (it infects one third
of the world's population) affecting mostly developing countries, including India, and recently …