Acute lymphoblastic leukemia (ALL) is a hematologic malignancy that predominantly occurs
in children between 2 and 10 years of age. L-asparaginase is an integral component of …

Asparaginase is an integral component of multiagent chemotherapy regimens for the
treatment of children with acute lymphoblastic leukemia. Positive outcomes are seen in …

Asparaginases are a cornerstone of treatment protocols for acute lymphoblastic leukemia
(ALL) and are used for remission induction and intensification treatment in all pediatric …

Pediatric Acute Lymphoblastic Leukemia (ALL) cure rates have improved exponentially over
the past five decades with now over 90% of children achieving long-term survival. A direct …

Abstract l-Asparaginase (EC3. 5.1. 1) is an enzyme, which is used for treatment of acute
lymphoblastic leukaemia (ALL) and other related blood cancers from a long time. This …

Cancer is caused by uncontrollable growth of neoplastic cells, leading to invasion of
adjacent and distant tissues resulting in death. Cancer cells have specific nutrient (s) …

l-asparaginase (ASNase, EC 3.5. 1.1) is an aminohydrolase enzyme with important uses in
the therapeutic/pharmaceutical and food industries. Its main applications are as an …

This study prospectively analyzed the efficacy of very prolonged courses of pegylated
Escherichia coli asparaginase (PEGasparaginase) and Erwinia asparaginase in pediatric …

This article comprises detailed information about L-asparaginase, encompassing topics
such as microbial and plant sources of L-asparaginase, treatment with L-asparaginase …

Asparaginase is widely used in chemotherapeutic regimens for the treatment of acute
lymphoblastic leukemia (ALL) and has led to a substantial improvement in cure rates …