[HTML][HTML] Epithelial-mesenchymal transition in cancer: a historical overview

D Ribatti, R Tamma, T Annese - Translational oncology, 2020 - Elsevier
Abstract Epithelial-mesenchymal transitions (EMTs), the acquisition of mesenchymal
features from epithelial cells, occur during some biological processes and are classified into …

[HTML][HTML] Role of tumor microenvironment in tumorigenesis

M Wang, J Zhao, L Zhang, F Wei, Y Lian, Y Wu… - Journal of …, 2017 - ncbi.nlm.nih.gov
Tumorigenesis is a complex and dynamic process, consisting of three stages: initiation,
progression, and metastasis. Tumors are encircled by extracellular matrix (ECM) and …

A pan-cancer mycobiome analysis reveals fungal involvement in gastrointestinal and lung tumors

AB Dohlman, J Klug, M Mesko, IH Gao, SM Lipkin… - Cell, 2022 - cell.com
Fungal microorganisms (mycobiota) comprise a small but immunoreactive component of the
human microbiome, yet little is known about their role in human cancers. Pan-cancer …

Cancer drug resistance induced by EMT: novel therapeutic strategies

J De Las Rivas, A Brozovic, S Izraely, A Casas-Pais… - Archives of …, 2021 - Springer
Over the last decade, important clinical benefits have been achieved in cancer patients by
using drug-targeting strategies. Nevertheless, drug resistance is still a major problem in …

Role of interleukin-6 in cancer progression and therapeutic resistance

N Kumari, BS Dwarakanath, A Das, AN Bhatt - Tumor Biology, 2016 - Springer
In the last several decades, the number of people dying from cancer-related deaths has not
reduced significantly despite phenomenal advances in the technologies related to diagnosis …

EMT and inflammation: inseparable actors of cancer progression

M Suarez‐Carmona, J Lesage, D Cataldo… - Molecular …, 2017 - Wiley Online Library
Tumors can be depicted as wounds that never heal, and are infiltrated by a large array of
inflammatory and immune cells. Tumor‐associated chronic inflammation is a hallmark of …

Hypoxia-induced epithelial-mesenchymal transition in cancers: HIF-1α and beyond

SY Tam, VWC Wu, HKW Law - Frontiers in oncology, 2020 - frontiersin.org
Metastasis is the main cause of cancer-related mortality. Although the actual process of
metastasis remains largely elusive, epithelial-mesenchymal transition (EMT) has been …

[HTML][HTML] The significant role of interleukin-6 and its signaling pathway in the immunopathogenesis and treatment of breast cancer

A Masjedi, V Hashemi, M Hojjat-Farsangi… - Biomedicine & …, 2018 - Elsevier
Despite remarkable improvements in cancer treatment approaches, breast cancer is still the
main cause of cancer-related death in women. Its principal cause is the resistance of the …

New insights into the role of EMT in tumor immune escape

S Terry, P Savagner, S Ortiz‐Cuaran… - Molecular …, 2017 - Wiley Online Library
Novel immunotherapy approaches have provided durable remission in a significant number
of cancer patients with cancers previously considered rapidly lethal. Nonetheless, the high …

Crosstalk between ferroptosis and the epithelial-mesenchymal transition: Implications for inflammation and cancer therapy

N Ebrahimi, S Adelian, S Shakerian… - Cytokine & growth factor …, 2022 - Elsevier
Both genomic instability and the presence of chronic inflammation are involved in
carcinogenesis and tumor progression. These alterations predispose the cancer cells to …