In this review, we provide an overview of protein synthesis in the yeast Saccharomyces
cerevisiae. The mechanism of protein synthesis is well conserved between yeast and other …

Abstract The SnRK1 (SNF1-related kinase 1) kinases are the plant cellular fuel gauges,
activated in response to energy-depleting stress conditions to maintain energy homeostasis …

Growing cells coordinate protein translation with metabolic rates. Central to this coordination
is ribosome production. Ribosomes drive cell growth, but translation of ribosomal proteins …

Understanding the regulation and structure of ribosomes is essential to understanding
protein synthesis and its dysregulation in disease. While ribosomes are believed to have a …

Cells respond to different types of stress by inhibition of protein synthesis and subsequent
assembly of stress granules (SGs), cytoplasmic aggregates that contain stalled translation …

Cellular responses to environmental stress are frequently mediated by RNA-binding
proteins (RBPs). Here, we examined global RBP dynamics in Saccharomyces cerevisiae in …

Mitochondrial stress requires timely intervention to prevent mitochondrial and cellular
dysfunction. Re-establishing the correct protein homeostasis is crucial for coping with …

The production of recombinant proteins is frequently enhanced at the levels of transcription,
codon usage, protein folding and secretion. Overproduction of heterologous proteins …

The budding yeast Saccharomyces cerevisiae must dynamically alter the composition of its
proteome in order to respond to diverse stresses. The reprogramming of gene expression …

Heat-shocked cells prioritize the translation of heat shock (HS) mRNAs, but the underlying
mechanism is unclear. We report that HS in budding yeast induces the disassembly of the …