The optimization of upstream and downstream processes for production of recombinant
adeno-associated virus (rAAV) with consistent quality depends on the ability to rapidly …

Vaccination is the most effective method of disease prevention and control. Many viruses
and bacteria that once caused catastrophic pandemics (eg, smallpox, poliomyelitis …

Affinity chromatography is among the most powerful separation techniques, achieving the
finest separation with high yields even in the most challenging feed streams. Incorporating …

The emergence of a new strain of coronavirus in late 2019, SARS-CoV-2, led to a global
pandemic in 2020. This may have been preventable if large scale, rapid diagnosis of active …

Introduction Effective cell-based production processes of virus particles are the foundation
for the global availability of classical vaccines, gene therapeutic vectors, and viral oncolytic …

Quantification of the multivalent interactions of influenza viruses binding at interfaces may
provide ways to tackle key biological questions regarding influenza virulence and zoonoses …

Influenza A viruses are dynamically epidemic and genetically diverse. Due to the antigenic
drift and shift of the virus, seasonal vaccines are required to be reformulated annually to …

Currently, marketed influenza vaccines are only efficient against homologous viruses, thus
requiring a seasonal update based on circulating subtypes. This constant reformulation …

Surface plasmon resonance (SPR)-based biosensors have emerged as a powerful platform
for bioprocess monitoring due to their ability to detect biointeractions in real time, without the …

Seasonal and pandemic influenza outbreaks present severe health and economic burdens.
To overcome limitations on influenza vaccines' availability and effectiveness, researchers …