Proteinaceous nanometer-scale pores are ubiquitous in biology. The canonical ionic
channels (eg, those that transport Na+, K+, Ca 2+, and Cl− across cell membranes) play key …

The unzipping kinetics for lesion-containing DNA duplexes was studied in an α-hemolysin (α-
HL) nanopore. The lesion of focus was the guanine two-electron oxidation product, 8-oxo-7 …

A striking feature of the α-hemolysin channel a prime candidate for biotechnological
applications is the dependence of its ionic conductance on the magnitude and direction of …

Human telomeric DNA consists of tandem repeats of the sequence 5′-TTAGGG-3′,
including a 3′ terminal single-stranded overhang of 100–200 nucleotides that can fold into …

Electrophoretic transport through a solid-state nanodevice comprised of two stacked
nanopore sensors is used to determine the free-solution mobility of DNA molecules based …

Nanopore technology holds high potential for next‐generation DNA sequencing. This
method operates by drawing an individual single‐stranded DNA molecule through a …

Translocation measurements of intact DNA strands with the ion channel α-hemolysin (α-HL)
are limited to single-stranded DNA (ssDNA) experiments as the dimensions of the channel …

Studies on the interaction of hairpin DNA with the α-hemolysin (α-HL) nanopore have
determined hairpin unzipping kinetics, thermodynamics, and sequence-dependent …

This article explores the role of some geometrical factors on the electrophoretically driven
translocations of macromolecules through nanopores. In the case of asymmetric pores, we …

The influence of DNA duplex structural destabilization introduced by a single base-pair
modification was investigated by nanopore measurements. A series of 11 modified base …