MTHFR gene polymorphisms and susceptibility to rheumatoid arthritis: a meta-analysis based on 16 studies
Z Bagheri-Hosseinabadi, D Imani, H Yousefi… - Clinical …, 2020 - Springer
Rheumatoid arthritis (RA) is the most common autoimmune rheumatic disease, in which an
epigenetic implication in the disease etiopathogenesis has been noted. Here in this meta …
epigenetic implication in the disease etiopathogenesis has been noted. Here in this meta …
MTHFR gene polymorphisms in diabetes mellitus
Y Cai, B Liu, Y Zhang, Y Zhou - Clinica Chimica Acta, 2024 - Elsevier
The methylenetetrahydrofolate reductase (MTHFR), methionine synthase (MTR), and
methionine synthase reductase (MTRR) are three regulatory enzymes in the folic acid (FA) …
methionine synthase reductase (MTRR) are three regulatory enzymes in the folic acid (FA) …
Genetic association and computational analysis of MTHFR gene polymorphisms rs1801131 and rs1801133 with breast cancer in the Bangladeshi population
Methylenetetrahydrofolate reductase (MTHFR) plays a crucial role in regulating one-carbon
metabolism. Polymorphisms within the MTHFR gene have been found to increase the risk of …
metabolism. Polymorphisms within the MTHFR gene have been found to increase the risk of …
MTRR A66G, RFC1 G80A, and MTHFR C677T and A1298C Polymorphisms and Disease Activity in Mexicans with Rheumatoid Arthritis Treated with Methotrexate
MG González-Mercado, F Rivas… - Genetic testing and …, 2017 - liebertpub.com
Aim: To investigate the relationships of polymorphisms in genes whose protein products are
related in the metabolic pathway of folic acid, particularly MTRR A66G, RFC1 G80A, and …
related in the metabolic pathway of folic acid, particularly MTRR A66G, RFC1 G80A, and …
Methotrexate elimination and toxicity: MTHFR 677C>T polymorphism in patients with primary CNS lymphoma treated with high‐dose methotrexate
YJ Choi, H Park, JS Lee, JY Lee, S Kim… - Hematological …, 2017 - Wiley Online Library
The genetic association of the methylenetetrahydrofolate reductase gene (MTHFR) 677C> T
polymorphism with methotrexate (MTX)‐associated toxicity has been evaluated and …
polymorphism with methotrexate (MTX)‐associated toxicity has been evaluated and …
Drug Metabolizing Enzymes: An Exclusive Guide into Latest Research in Pharmaco-genetic Dynamics in Arab Countries
Drug metabolizing enzymes play a crucial role in the pharmacokinetics and
pharmacodynamics of therapeutic drugs, influencing their efficacy and safety. This review …
pharmacodynamics of therapeutic drugs, influencing their efficacy and safety. This review …
Associations of methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms with genetic susceptibility to rheumatoid arthritis: a meta-analysis
H Cen, H Huang, LN Zhang, LY Liu, L Zhou, XF Xin… - Clinical …, 2017 - Springer
The aim of our study was to conduct a meta-analysis to assess whether combined evidence
shows associations between C677T and A1298C polymorphisms of …
shows associations between C677T and A1298C polymorphisms of …
Associations between C677T and A1298C polymorphisms of MTHFR and susceptibility to rheumatoid arthritis: a systematic review and meta-analysis
Y Yuan, W Shao, Y Li - Rheumatology international, 2017 - Springer
Methylenetetrahydrofolatereductase (MTHFR) is an important enzyme involved in folate
metabolism and DNA synthesis. Although a number of studies have examined the …
metabolism and DNA synthesis. Although a number of studies have examined the …
[HTML][HTML] The protective effects of the methylenetetrahydrofolate reductase rs1801131 variant among Saudi smokers
MH Almutairi, NS Al-Numair, NR Parine… - Saudi Journal of …, 2021 - Elsevier
Methylenetetrahydrofolate reductase (MTHFR) polymorphism plays a fundamental role in
susceptibility to various diseases, including cancers and autoimmune diseases. In the …
susceptibility to various diseases, including cancers and autoimmune diseases. In the …
Membrane‐Spanning Protein Genetic Polymorphisms Related to Methotrexate Therapeutic Outcomes in a Chinese Rheumatoid Arthritis Population
S Lv, H Fan, H Yang, J Huang, J Li… - The Journal of …, 2019 - Wiley Online Library
Methotrexate (MTX) is a first‐line disease‐modifying antirheumatic drug for rheumatoid
arthritis (RA), but individual variation in treatment response remains unexplained. The …
arthritis (RA), but individual variation in treatment response remains unexplained. The …