TFOS DEWS II sex, gender, and hormones report

DA Sullivan, EM Rocha, P Aragona, JA Clayton, J Ding… - The ocular …, 2017 - Elsevier
One of the most compelling features of dry eye disease (DED) is that it occurs more
frequently in women than men. In fact, the female sex is a significant risk factor for the …

[HTML][HTML] Effects of aging in dry eye

CS de Paiva - International ophthalmology clinics, 2017 - journals.lww.com
Tear dysfunction is one of the most common problems encountered by eye doctors. Tear
dysfunction has a reported prevalence ranging from 2% to 14.2%. 1–3 It has been found to …

The ocular surface immune system through the eyes of aging

JG Galletti, CS de Paiva - The ocular surface, 2021 - Elsevier
Since the last century, advances in healthcare, housing, and education have led to an
increase in life expectancy. Longevity is accompanied by a higher prevalence of age-related …

[HTML][HTML] The role of oxidative stress in the aging eye

D Goodman, S Ness - Life, 2023 - mdpi.com
Given the expanding elderly population in the United States and the world, it is important to
understand the processes underlying both natural and pathological age-related changes in …

[HTML][HTML] Nampt expression decreases age-related senescence in rat bone marrow mesenchymal stem cells by targeting Sirt1

C Ma, C Pi, Y Yang, L Lin, Y Shi, Y Li, Y Li, X He - PloS one, 2017 - journals.plos.org
Senescence restricts the development of applications involving mesenchymal stem cells
(MSCs) in research fields, such as tissue engineering, and stem cell therapeutic strategies …

[PDF][PDF] Age-related autoimmune changes in lacrimal glands

RG de Souza, CS de Paiva, MR Alves - Immune network, 2019 - synapse.koreamed.org
Aging is a complex process associated with dysregulation of the immune system and low
levels of inflammation, often associated with the onset of many pathologies. The lacrimal …

Age-related ocular surface failure: A narrative review

A Di Zazzo, M Coassin, PL Surico, S Bonini - Experimental Eye Research, 2022 - Elsevier
Ageing has been defined as a specific individual plasticity and remodeling capacity to the
environment'insults and stimuli. The precise physiology of aging is not entirely understood …

Therapeutic strategies to treat dry eye in an aging population

NS Ezuddin, KA Alawa, A Galor - Drugs & aging, 2015 - Springer
Dry eye (DE) is a prevalent ocular disease that primarily affects the elderly. Affecting up to
30% of adults aged 50 years and older, DE affects both visual function and quality of life …

Presbyopia and the aging eye: Existing refractive approaches and their potential impact on dry eye signs and symptoms

E Lafosse, JS Wolffsohn, C Talens-Estarelles… - Contact Lens and …, 2020 - Elsevier
Every part of the human body is subject to aging, including the eye. An increased
prevalence of dry eye disease with age is widely acknowledged. Aging threatens ocular …

[HTML][HTML] Prevalence of dry eye disease in the elderly: A protocol of systematic review and meta-analysis

X Zhang, L Wang, Y Zheng, L Deng, X Huang - Medicine, 2020 - journals.lww.com
Results: The results of this study will systematically evaluate the prevalence of DED in the
elderly population over 60 years of age. Conclusion: The systematic review of this study will …