The architects of bacterial DNA bridges: a structurally and functionally conserved family of proteins

L Qin, AM Erkelens, F Ben Bdira… - Open biology, 2019 - royalsocietypublishing.org
Every organism across the tree of life compacts and organizes its genome with architectural
chromatin proteins. While eukaryotes and archaea express histone proteins, the …

Regulation of gram-positive conjugation

V Kohler, W Keller, E Grohmann - Frontiers in microbiology, 2019 - frontiersin.org
Type IV Secretion Systems (T4SSs) are membrane-spanning multiprotein complexes
dedicated to protein secretion or conjugative DNA transport (conjugation systems) in …

Plasmid-encoded ComI inhibits competence in the ancestral 3610 strain of Bacillus subtilis

MA Konkol, KM Blair, DB Kearns - Journal of Bacteriology, 2013 - Am Soc Microbiol
Natural competence is a process by which bacteria construct a membrane-associated
machine for the uptake and integration of exogenous DNA. Many bacteria harbor genes for …

Vibrio cholerae combines individual and collective sensing to trigger biofilm dispersal

PK Singh, S Bartalomej, R Hartmann, H Jeckel… - Current Biology, 2017 - cell.com
Bacteria can generate benefits for themselves and their kin by living in multicellular, matrix-
enclosed communities, termed biofilms, which are fundamental to microbial ecology and the …

The B. subtilis Rok protein is an atypical H-NS-like protein irresponsive to physico-chemical cues

AM Erkelens, L Qin, B van Erp… - Nucleic Acids …, 2022 - academic.oup.com
Nucleoid-associated proteins (NAPs) play a central role in chromosome organization and
environment-responsive transcription regulation. The Bacillus subtilis-encoded NAP Rok …

Mobility of the Native Bacillus subtilis Conjugative Plasmid pLS20 Is Regulated by Intercellular Signaling

PK Singh, G Ramachandran, R Ramos-Ruiz… - PLoS …, 2013 - journals.plos.org
Horizontal gene transfer mediated by plasmid conjugation plays a significant role in the
evolution of bacterial species, as well as in the dissemination of antibiotic resistance and …

Multiple Layered Control of the Conjugation Process of the Bacillus subtilis Plasmid pLS20

WJJ Meijer, DR Boer, S Ares, C Alfonso… - Frontiers in Molecular …, 2021 - frontiersin.org
Bacterial conjugation is the main horizontal gene transfer route responsible for the spread of
antibiotic resistance, virulence and toxin genes. During conjugation, DNA is transferred from …

Manipulation of natural transformation by AbaR-type islands promotes fixation of antibiotic resistance in Acinetobacter baumannii

R Tuffet, G Carvalho, AS Godeux… - Proceedings of the …, 2024 - pnas.org
The opportunistic pathogen Acinetobacter baumannii, carries variants of A. baumannii
resistance islands (AbaR)-type genomic islands conferring multidrug resistance. Their …

Competence and transformation in Bacillus subtilis

B Maier - Current Issues in Molecular Biology, 2020 - mdpi.com
Transformation is the process of import and inheritable integration of DNA from the
environment. As such, it is believed to be a major driving force for evolution. Competence for …

Discovery of a new family of relaxases in Firmicutes bacteria

G Ramachandran, A Miguel-Arribas, D Abia… - PLoS …, 2017 - journals.plos.org
Antibiotic resistance is a serious global problem. Antibiotic resistance genes (ARG), which
are widespread in environmental bacteria, can be transferred to pathogenic bacteria via …