[HTML][HTML] The neural circuitry of social homeostasis: Consequences of acute versus chronic social isolation

CR Lee, A Chen, KM Tye - Cell, 2021 - cell.com
Social homeostasis is the ability of individuals to detect the quantity and quality of social
contact, compare it to an established set-point in a command center, and adjust the effort …

Endocrine cybernetics: neuropeptides as molecular switches in behavioural decisions

DR Nässel, M Zandawala - Open Biology, 2022 - royalsocietypublishing.org
Plasticity in animal behaviour relies on the ability to integrate external and internal cues from
the changing environment and hence modulate activity in synaptic circuits of the brain. This …

The Drosophila toll pathway in innate immunity: from the core pathway toward effector functions

S Valanne, L Vesala, MK Maasdorp… - The Journal of …, 2022 - journals.aai.org
The fruit fly Drosophila melanogaster Toll signaling pathway has an evolutionarily
conserved role in controlling immune responses. Whereas the microbial recognition …

Long-term impact of social isolation and molecular underpinnings

RG Arzate-Mejía, Z Lottenbach, V Schindler… - Frontiers in …, 2020 - frontiersin.org
Prolonged periods of social isolation can have detrimental effects on the physiology and
behavior of exposed individuals in humans and animal models. This involves complex …

[HTML][HTML] Isolation disrupts social interactions and destabilizes brain development in bumblebees

ZY Wang, GC McKenzie-Smith, W Liu, HJ Cho… - Current Biology, 2022 - cell.com
Social isolation, particularly in early life, leads to deleterious physiological and behavioral
outcomes. Here, we leverage new high-throughput tools to comprehensively investigate the …

How Social Experience and Environment Impacts Behavioural Plasticity in Drosophila

M Chen, MB Sokolowski - Fly, 2022 - Taylor & Francis
An organism's behaviour is influenced by its social environment. Experiences such as social
isolation or crowding may have profound short or long-term effects on an individual's …

A neural pathway for social modulation of spontaneous locomotor activity (SoMo-SLA) in Drosophila

H Zhao, X Jiang, M Ma, L Xing… - Proceedings of the …, 2024 - National Acad Sciences
Social enrichment or social isolation affects a range of innate behaviors, such as sex,
aggression, and sleep, but whether there is a shared mechanism is not clear. Here, we …

Sight of parasitoid wasps accelerates sexual behavior and upregulates a micropeptide gene in Drosophila

SAM Ebrahim, GJS Talross, JR Carlson - Nature Communications, 2021 - nature.com
Parasitoid wasps inflict widespread death upon the insect world. Hundreds of thousands of
parasitoid wasp species kill a vast range of insect species. Insects have evolved defensive …

Effects of social isolation on the development of anxiety and depression-like behavior in model experiments in animals

GA Grigoryan, IV Pavlova, MI Zaichenko - Neuroscience and behavioral …, 2022 - Springer
This review describes the role of social isolation in the development of anxiety and
depression-like behavior in rodents. The duration of social isolation, age from onset of social …

The impact of social isolation on health and behavior in Drosophila melanogaster and beyond

A Vora, AD Nguyen, C Spicer… - Brain Science Advances, 2022 - journals.sagepub.com
Many organisms, including humans, have evolved dynamic social behaviors to promote
survival. Public health studies show that isolation from social groups is a major risk factor for …