NMR spectroscopy has been applied to cells and tissues analysis since its beginnings, as early as 1950. We have attempted to gather here in a didactic fashion the broad diversity of …
AB Schmidt, CR Bowers, K Buckenmaier… - Analytical …, 2022 - ACS Publications
The unique properties of the entangled, antisymmetric nuclear spin state of dihydrogen, parahydrogen (pH2), has intrigued physicists, chemists, and other scientists for almost a …
Molecular metabolic imaging in humans is dominated by positron emission tomography (PET). An emerging nonionizing alternative is hyperpolarized MRI of 13C-pyruvate, which is …
Hyperpolarized fumarate is a promising biosensor for carbon-13 magnetic resonance metabolic imaging. Such molecular imaging applications require nuclear hyperpolarization …
A Fürstner - Journal of the American Chemical Society, 2018 - ACS Publications
cis-Delivery of H2 to the π-system of an unsaturated substrate is the canonical course of metal catalyzed hydrogenation reactions. The semireduction of internal alkynes with the aid …
G Buntkowsky, F Theiss, J Lins, YA Miloslavina… - RSC …, 2022 - pubs.rsc.org
Nuclear Magnetic Resonance (NMR) spectroscopy and Magnetic Resonance Imaging (MRI) are analytical and diagnostic tools that are essential for a very broad field of applications …
M Gierse, L Nagel, M Keim, S Lucas… - Journal of the …, 2023 - ACS Publications
We present a versatile method for the preparation of hyperpolarized [1-13C] fumarate as a contrast agent for preclinical in vivo MRI, using parahydrogen-induced polarization (PHIP) …
Parahydrogen‐induced polarization with heterogeneous catalysts (HET‐PHIP) has been a subject of extensive research in the last decade since its first observation in 2007. While …
ParaHydrogen induced polarization (PHIP) is an efficient and cost-effective hyperpolarization method, but its application to biological investigations has been …