Effects of ferroptosis on male reproduction

Y Liu, X Cao, C He, X Guo, H Cai, A Aierken… - International journal of …, 2022 - mdpi.com
Ferroptosis is a relatively novel form of regulated cell death that was discovered in 2012.
With the increasing research related to the mechanisms of ferroptosis, previous studies have …

[HTML][HTML] The interplay of arsenic, silymarin, and NF-ĸB pathway in male reproductive toxicity: A review

AG Mukherjee, AV Gopalakrishnan - Ecotoxicology and Environmental …, 2023 - Elsevier
Arsenic toxicity is one of the most trending reasons for several malfunctions, particularly
reproductive toxicity. The exact mechanism of arsenic poisoning is a big question mark …

Arsenite induces testicular oxidative stress in vivo and in vitro leading to ferroptosis

P Meng, S Zhang, X Jiang, S Cheng, J Zhang… - Ecotoxicology and …, 2020 - Elsevier
Ferroptosis is a newly identified form of cell death characterized by accumulation of
intracellular iron and requirement of lipid peroxidation. However, whether arsenite triggers …

The mechanisms of arsenic-induced ovotoxicity, ultrastructural alterations, and autophagic related paths: An enduring developmental study in folliculogenesis of mice

MM Ommati, X Shi, H Li, MJ Zamiri, O Farshad… - Ecotoxicology and …, 2020 - Elsevier
Arsenic (As) exerts a wide range of adverse effects on biological systems, including the
reproductive organs in males and females. However, the mechanisms of As-induced …

Review on molecular and biochemical insights of arsenic-mediated male reproductive toxicity

K Renu, H Madhyastha, R Madhyastha, M Maruyama… - Life sciences, 2018 - Elsevier
Arsenic is a natural metalloid found in abundance, in the environment. Exposure to arsenic
can cause health issues due to its carcinogenic nature. The primary source of arsenic …

Paternal exposure to arsenic resulted in oxidative stress, autophagy, and mitochondrial impairments in the HPG axis of pubertal male offspring

MM Ommati, R Heidari, RK Manthari, ST Chiranjeevi… - Chemosphere, 2019 - Elsevier
Despite the knowledge of AS-induced reprotoxicity, the literature concerning arsenic trioxide
(As 2 O 3)-induced oxidative stress and consequent intracellular events, like autophagy …

Integrated proteomics and metabolomics analysis of rat testis: mechanism of arsenic-induced male reproductive toxicity

Q Huang, L Luo, A Alamdar, J Zhang, L Liu, M Tian… - Scientific reports, 2016 - nature.com
Arsenic is a widespread metalloid in environment, whose exposure has been associated
with a broad spectrum of toxic effects. However, a global view of arsenic-induced male …

Arsenic-induced autophagic alterations and mitochondrial impairments in HPG-S axis of mature male mice offspring (F1-generation): A persistent toxicity study

MM Ommati, RK Manthari, C Tikka, R Niu, Z Sun… - Toxicology letters, 2020 - Elsevier
Arsenic (As) has been implicated in causing reproductive toxicity, but the precise cellular
pathway through which the As toxicity in mature F1-male mice hypothalamic-pituitary …

Multi-omics analyses reveal the mechanisms of Arsenic-induced male reproductive toxicity in mice

Z Peng, Q Yang, R Yeerken, J Chen, X Liu… - Journal of Hazardous …, 2022 - Elsevier
Arsenic (As), a widespread environmental contaminant, can induce serious male
reproductive injury; however, the underlying mechanisms remain unclear. Multi-omics …

Contemporary comprehensive review on arsenic-induced male reproductive toxicity and mechanisms of phytonutrient intervention

M Rachamalla, J Chinthada, S Kushwaha, SK Putnala… - Toxics, 2022 - mdpi.com
Arsenic (As) is a poisonous metalloid that is toxic to both humans and animals. Drinking
water contamination has been linked to the development of cancer (skin, lung, urinary …