There is now overwhelming evidence to support lowering LDL-c (low-density lipoprotein
cholesterol) to reduce cardiovascular morbidity and mortality. Statins are a class of drugs …

Abstract Treatment with statins, inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A
reductase, has proven beneficial preventive effects on cardiovascular events. However …

Statins reduce cholesterol, prevent cardiovascular disease, and are among the most
commonly prescribed medications in the world. Statin‐associated musculoskeletal …

Statins are a family of drugs that are used for treating hyperlipidaemia with a recognized
capacity to prevent cardiovascular disease events. They inhibit β‐hydroxy β‐methylglutaryl …

Hyperlipidemia is a major risk factor for cardiovascular morbidity and mortality. Statins are
the first-choice therapy for dyslipidemias and are considered the cornerstone of …

Coenzyme Q (CoQ) is an essential component of the mitochondrial electron transport chain
and an antioxidant in plasma membranes and lipoproteins. It is endogenously produced in …

Parkinson's disease (PD) is a neurodegenerative disease characterized by a progressive
loss of dopaminergic neurons from the nigrostriatal pathway, formation of Lewy bodies, and …

Statins are a cornerstone in the pharmacological prevention of cardiovascular disease.
Although generally well tolerated, a small subset of patients experience statin-related …

Abstract The Canadian Consensus Working Group has updated its evaluation of the
literature pertaining to statin intolerance and adverse effects. This overview introduces a …

Objective: To validate new mitochondrial myopathy serum biomarkers for diagnostic use.
Methods: We analyzed serum FGF21 (S-FGF21) and GDF15 from patients with (1) …