The obesity-breast cancer link: a multidisciplinary perspective

EN Devericks, MS Carson, LE McCullough… - Cancer and Metastasis …, 2022 - Springer
Obesity, exceptionally prevalent in the USA, promotes the incidence and progression of
numerous cancer types including breast cancer. Complex, interacting metabolic and …

TFOS DEWS II sex, gender, and hormones report

DA Sullivan, EM Rocha, P Aragona, JA Clayton, J Ding… - The ocular …, 2017 - Elsevier
One of the most compelling features of dry eye disease (DED) is that it occurs more
frequently in women than men. In fact, the female sex is a significant risk factor for the …

C-reactive protein in healthy subjects: associations with obesity, insulin resistance, and endothelial dysfunction: a potential role for cytokines originating from adipose …

JS Yudkin, CDA Stehouwer, JJ Emeis… - … , and vascular biology, 1999 - Am Heart Assoc
C-reactive protein, a hepatic acute phase protein largely regulated by circulating levels of
interleukin-6, predicts coronary heart disease incidence in healthy subjects. We have shown …

Elevated C-reactive protein levels in overweight and obese adults

M Visser, LM Bouter, GM McQuillan, MH Wener… - Jama, 1999 - jamanetwork.com
ContextHuman adipose tissue expresses and releases the proinflammatory cytokine
interleukin 6, potentially inducing low-grade systemic inflammation in persons with excess …

Subcutaneous Adipose Tissue Releases Interleukin-6, But Not Tumor Necrosis Factor-α, in Vivo

V Mohamed-Ali, S Goodrick, A Rawesh… - The Journal of …, 1997 - academic.oup.com
We measured arterio-venous differences in concentrations of tumor necrosis factor-α (TNFα)
and interleukin-6 (IL-6) across a sc adipose tissue bed in the postabsorptive state in 39 …

Omental and subcutaneous adipose tissues of obese subjects release interleukin-6: depot difference and regulation by glucocorticoid

SK Fried, DA Bunkin… - The Journal of Clinical …, 1998 - academic.oup.com
The purpose of this study was to determine whether human adipocytes from different depots
of obese subjects produce interleukin-6 (IL-6) and whether IL-6 release is regulated by …

Adipocyte biology in breast cancer: From silent bystander to active facilitator

J Choi, YJ Cha, JS Koo - Progress in lipid research, 2018 - Elsevier
Adipocytes account for the largest proportion among the cells that comprise breast tissue;
therefore, they are considered to be a critical cell type in the tumor microenvironment of …

[HTML][HTML] Circulating inflammatory markers in polycystic ovary syndrome: a systematic review and metaanalysis

HF Escobar-Morreale, M Luque-Ramírez, F González - Fertility and sterility, 2011 - Elsevier
OBJECTIVE: To perform a review and metaanalysis of the studies evaluating the status of
serum inflammatory markers in women with polycystic ovary syndrome (PCOS). DESIGN …

Inflammation, obesity, stress and coronary heart disease: is interleukin-6 the link?

JS Yudkin, M Kumari, SE Humphries, V Mohamed-Ali - Atherosclerosis, 2000 - Elsevier
There is mounting evidence that inflammation plays a role in the development of coronary
heart disease (CHD). Observations have been made linking the presence of infections in the …

Pro-inflammatory cytokines and adipose tissue

SW Coppack - Proceedings of the nutrition society, 2001 - cambridge.org
Cytokines appear to be major regulators of adipose tissue metabolism. Therapeutic
modulation of cytokine systems offers the possibility of major changes in adipose tissue …