Cryptococcal therapies and drug targets: the old, the new and the promising

C Coelho, A Casadevall - Cellular microbiology, 2016 - Wiley Online Library
Half a century after the introduction of Amphotericin B the management of cryptococcosis
remains unsatisfactory. The disease, caused primarily by the two fungal species …

Environmental triazole induces cross-resistance to clinical drugs and affects morphophysiology and virulence of Cryptococcus gattii and C. neoformans

RW Bastos, HCS Carneiro, LVN Oliveira… - Antimicrobial agents …, 2018 - Am Soc Microbiol
Cryptococcus gattii and Cryptococcus neoformans are environmental fungi that cause
cryptococcosis, which is usually treated with amphotericin B and fluconazole. However …

Cinnamyl Schiff bases: Synthesis, cytotoxic effects and antifungal activity of clinical interest

TFF Magalhães, CM Da Silva… - Letters in Applied …, 2020 - academic.oup.com
The aim of this study was to synthesize and investigate the in vitro antifungal properties of 23
cinnamyl Schiff bases. In addition, cytotoxic effects of such cinnamyl Schiff bases against …

Synthesis, crystal structures, and application of two new pincer type palladium (II)-Schiff base complexes in CC cross-coupling reactions

B Agrahari, S Layek, R Ganguly, DD Pathak - Inorganica Chimica Acta, 2018 - Elsevier
Two new pincer type Pd (II)-Schiff base complexes of the general formula [PdL 1 (PPh 3)] 1
and [PdL 2 (PPh 3)] 2,(where L 1= 2-(2, 3-Dihydroxybenzylideneamino) phenolate and L 2 …

Synthesis, characterization and single crystal X-ray studies of pincer type Ni (II)-Schiff base complexes: Application in synthesis of 2-substituted benzimidazoles

B Agrahari, S Layek, R Ganguly, N Dege… - Journal of Organometallic …, 2019 - Elsevier
Five new pincer type Ni (II)-Schiff base complexes of the general formula [NiL 1 (PPh 3)]
1,[NiL 2 (PPh 3)] 2,[NiL 3 (PPh 3)] 3,[NiL 4 (PPh 3)] 4 and [NiL 4 (4-MePy)] 5 [where H 2 L 1 …

Thiazole compounds with activity against Cryptococcus gattii and Cryptococcus neoformans in vitro

NP de Sá, CI Lino, NC Fonseca, BM Borelli… - European Journal of …, 2015 - Elsevier
Human cryptococcosis can occur as a primary or opportunistic infection and develop as an
acute, subacute, or chronic, systemic infection involving different host organs. We evaluated …

From the environment to the host: how non-azole agrochemical exposure affects the antifungal susceptibility and virulence of Cryptococcus gattii

RW Bastos, GJC Freitas, HCS Carneiro… - Science of the Total …, 2019 - Elsevier
Agrochemicals such as the non-azoles, used to improve crop productivity, poses severe
undesirable effects on the environment and human health. In addition, they induce cross …

A new acridone with antifungal properties against Candida spp. and dermatophytes, and antibiofilm activity against C. albicans

DBC de Oliveira, LB Silva, BV da Silva… - Journal of applied …, 2019 - academic.oup.com
Aim The increase in the number of fungal infections worldwide, coupled with the limitations
of current antifungal chemotherapy, demand the development of safe and effective new …

Do schiff bases-based urease inhibitors improve plant growth and affect the activity of soil arginase?

S Chaves-Silva, LP Horta, LT Souza… - Industrial crops and …, 2020 - Elsevier
The increase in nitrogen (N) use efficiency in acidic soils is necessary to boost the tropical
agriculture yields and mitigate N losses and the supplementation of urea-based fertilizers …

Antifungal activity of decyl gallate against several species of pathogenic fungi

ACA de Paula e Silva, CB Costa-Orlandi… - Evidence‐Based …, 2014 - Wiley Online Library
This work aims to demonstrate that the gallic acid structure modification to the decyl gallate
(G14) compound contributed to increase the antifungal activity against several species of …