Under normal conditions, the sympathetic neurotransmitter noradrenaline inhibits the
production and release of pro-inflammatory cytokines. However, after peripheral nerve and …

The Na+/H+ exchanger isoform 1 (NHE1) is a ubiquitously expressed transporter fulfilling a
variety of cell physiological tasks. By importing Na+ and exporting H+, NHE1 contributes to …

Protein arginine methylation is catalyzed by protein arginine methyltransferases (PRMTs)
and plays an important role in many cellular processes. Aberrant PRMT expression has …

Glioblastoma multiforme is the most aggressive form of primary brain tumor and remains
largely incurable, in large part, due to its highly invasive nature. The phosphoinositide (PI) 3 …

Objective—Stimulation of cardiac α1A-adrenergic receptors (α1A-AR) has been proposed
for treatment of heart failure, since it increases myocardial contractility. We investigated a …

Alpha-1 adrenoceptors are overexpressed in the epidermis of a subgroup of patients with
complex regional pain syndrome (CRPS). Activating a1-adrenoceptors in epidermal cells …

The sodium hydrogen exchanger isoform one (NHE1) plays a critical role coordinating
asymmetric events at the leading edge of migrating cells and is regulated by a number of …

Matrix metalloproteinase 9 (MMP-9) plays a critical role in digesting the extracellular matrix
and has a vital function in tumor metastasis and invasion; this protease activity is …

Stimulation of α 1-adrenoceptors evokes inflammatory cytokine production, boosts
neurogenic inflammation and pain, and influences cellular migration and proliferation. As …

Stimulation of α 1-adrenoceptors evokes inflammatory cytokine production, boosts
neurogenic inflammation and pain, and influences cellular migration and proliferation …