Despite considerable progress has been achieved in the treatment of acute myeloid
leukemia over the past decades, relapse remains a major problem. Novel therapeutic …

Natural killer (NK) cells are large granular lymphocytes involved in our defense against
certain virus-infected and malignant cells. In contrast to T cells, NK cells elicit rapid anti …

This review aims to summarize the anticancer effects of the natural monoterpene phenol
derivative of cymenethymol and its derivatives as well as further molecular docking study to …

Acute myeloid leukemia (AML) remains difficult to treat and requires new therapeutic
approaches. Potent inhibitors of the chromatin-associated protein MENIN have recently …

Acute myeloid leukemia (AML) remains an elusive disease to treat, let alone cure, even after
highly intensive therapies such as stem cell transplants. Adoptive cell therapeutic strategies …

The protein cereblon (CRBN) is a substrate receptor of the cullin 4-really interesting new
gene (RING) E3 ubiquitin ligase complex CRL4 CRBN. Targeting CRBN mediates selective …

Acute myeloid leukemia (AML) is a hematologic malignancy that frequently relapses, even if
remission can be achieved with intensive chemotherapy. One known relapse mechanism is …

Due to their physiological role in removing damaged cells, natural killer (NK) cells represent
ideal candidates for cellular immunotherapy in the treatment of cancer. Thereby, the …

Over recent years, tremendous advances in immunotherapy approaches have been
observed, generating significant clinical progress. Cancer immunotherapy has been shown …

Acute myeloid leukemia (AML) is considered as one of the most malignant conditions of the
bone marrow. Over the past few decades, despite substantial progresses in the …