Extensive injury of endothelial cells in blood vasculature, especially in the microcirculatory
system, frequently occurs in hosts suffering from sepsis and the accompanied systemic …

As the population ages and lifestyles change in concordance, the number of patients
suffering from ischemic stroke and its associated disabilities is increasing. Studies on …

Abstract Background Endothelial progenitor cells (EPCs) are promising candidates for the
cellular therapy of peripheral arterial and cardiovascular diseases. However, hitherto there …

Cytokines are known for their pleiotropic effects. They can be classified by their function as
pro-inflammatory, such as tumor necrosis factor (TNF), interleukin (IL) 1 and IL-12, or anti …

Non-targeted effects (NTE) such as bystander effects or genomic instability have been
known for many years but their significance for radiotherapy or medical diagnostic radiology …

Shortly after the discovery of endothelial progenitor cells (EPCs) in 1997, many clinical trials
were conducted using EPCs as a cellular based therapy with the goal of restoring damaged …

Radiation-induced bystander effect (RIBE), eg the biological response occurring in
unirradiated cells when their neighboring cells are irradiated, is the consequence of …

Abstract Background/Aims: TGF-β1 mediated radiation-induced bystander effects (RIBE)
have been linked with malignant transformation and tumorigenesis. However, the underlying …

Radiation exposure to immune system induces imbalance in cytokines expression involved
in Th1/Th2 homeostasis perturbations. In the present study, N-acetyl tryptophan glucoside …

The cardiovascular biology of proton radiotherapy is not well understood. We aimed to
compare the genomic dose-response to proton and gamma radiation of the mouse aorta to …