Compositions comprising lipophilic active compounds and method for their preparation

GT Krayz, M Averbuch, I Zelkind, L Gitis - US Patent 9,254,268, 2016 - Google Patents
Compositions are provided comprising a lipophilic active compound, eg, a human or
veterinary drug or a nutraceuti cal, interwoven with a polymeric matrix formed by two or more …

Modified release compositions comprising tacrolimus

P Holm - US Patent 8,591,946, 2013 - Google Patents
USPC.................................................. 424/464 489 (7) ABSTRACT See application file for
complete search history. A modified release composition comprising tacrolimus releases …

Tacrolimus for improved treatment of transplant patients

RD Gordon, P Holm, AM Lademann… - US Patent 8,685,998, 2014 - Google Patents
An extended release oral dosage form comprising as active Substance tacrolimus or a
pharmaceutically active analogue thereof for a once daily immunosuppressive treatment of a …

Solid dispersions comprising tacrolimus

P Holm - US Patent 7,994,214, 2011 - Google Patents
US7994214B2 - Solid dispersions comprising tacrolimus - Google Patents US7994214B2 -
Solid dispersions comprising tacrolimus - Google Patents Solid dispersions comprising …

Microspheres comprising nanocapsules containing a lipophilic drug

S Benita, A Rom, T Nasser - US Patent 9,023,386, 2015 - Google Patents
The present invention provides microspheres comprising a plurality of nanocapsules
accommodated in a gel forming polymer, the plurality of nanocapsules comprising an oil …

Tacrolimus for improved treatment of transplant patients

RD Gordon, P Holm, AM Lademann… - US Patent 8,664,239, 2014 - Google Patents
An extended release oral dosage form comprising as active substance tacrolimus or a
pharmaceutically active analogue thereof for a once daily immunosuppressive treatment of a …

Modified release compositions comprising tacrolimus

P Holm, T Norling - US Patent 8,889,186, 2014 - Google Patents
Jun. 23, 2011, now Pat. No. 8,623,411, which is a FOREIGN PATENT DOCUMENTS
continuation of application No. 10/569,862, filed as EP O184162 A2 6, 1986 application No …

Modified release compositions comprising tacrolimus

P Holm, T Norling - US Patent 8,617,599, 2013 - Google Patents
(57) ABSTRACT A modified release composition comprising tacrolimus releases less than
20% w/w of the active ingredient within 0.5 hours when subjected to an invitro dissolution …

Modified release compositions comprising tacrolimus

P Holm, T Norling - US Patent 8,623,411, 2014 - Google Patents
5,601,844 A 2/1997 Kagayama et al. 6,168,806 B1 1/2001 Lee et al. 6,204.243 B1 3, 2001
Posanski 6,346,537 B1 2/2002 Hata et al. 6,387.918 B1 5/2002 Yamanaka et al. 6,440,458 …

Modified release compositions comprising tacrolimus

P Holm, T Norling - US Patent 8,586,084, 2013 - Google Patents
(57) ABSTRACT A modified release composition comprising tacrolimus releases less than
20% w/w of the active ingredient within 0.5 hours when subjected to an invitro dissolution …