Post-translational modifications (PTMs) are known to be essential mechanisms used by
eukaryotic cells to diversify their protein functions and dynamically coordinate their signaling …

Vitiligo is the most frequent human pigmentary disorder, characterized by progressive
autoimmune destruction of mature epidermal melanocytes. Of the current treatments offering …

The current utility of 3D skin equivalents is limited by the fact that existing models fail to
recapitulate the cellular complexity of human skin. They often contain few cell types and no …

Many studies have suggested the significance of glycosyltransferase-mediated
macromolecule glycosylation in the regulation of pluripotent states in human pluripotent …

Sarbecoviruses such as SARS and SARS-CoV-2 have been responsible for two major
outbreaks in humans, the latter resulting in a global pandemic. While sarbecoviruses …

This study investigates the utility of a tailored poly (ethylene glycol) diacrylate-crosslinked
porous polymeric tissue engineering scaffold, with mechanical properties specifically …

Induced pluripotent stem cells (iPSCs) are a promising melanocyte source as they
propagate indefinitely and can be established from patients. However, the in vivo functions …

Induced pluripotent stem cells (iPSC s) are considered patient‐specific counterparts of
embryonic stem cells as they originate from somatic cells after forced expression of …

Melanocytes in the skin play an indispensable role in the pigmentation of skin and its
appendages. It is well known that the embryonic origin of melanocytes is neural crest cells …

Vitiligo is an auto-immune disease, causing depigmentation of skin in 0.2-1.8% of global
population. Topical corticosteroids and calcineurin inhibitors are the only treatments with …