The nature of cancer control is changing, with an increasing emphasis, fuelled by public and
political demand, on prevention, early diagnosis, and patient experience during and after …

Purpose: Family history of colorectal cancer (CRC) is a known risk factor for CRC and
encompasses both genetic and shared environmental risks. Methods: We conducted a …

Scientific and technologic advances are revolutionizing our approach to genetic cancer risk
assessment, cancer screening and prevention, and targeted therapy, fulfilling the promise of …

Family history is a risk factor for many chronic diseases, including cancer, cardiovascular
disease, and diabetes. Professional guidelines usually include family history to assess …

Family health history (FHH) is the most useful means of assessing risk for common chronic
diseases. The odds ratio for risk of developing disease with a positive FHH is frequently …

Lynch syndrome is the most common cause of inherited colorectal and endometrial cancers
yet it is underrecognized in clinical practice. The relative merits of screening for Lynch …

Background A family history, reflecting genetic susceptibility as well as shared
environmental and behavioral factors, is an important risk factor for common chronic …

Objective Heterozygous familial hypercholesterolaemia (FH) is a common autosomal
dominant disorder. The vast majority of affected individuals remain undiagnosed, resulting in …

Background Although most neoplasms result from complex interactions between the
individual's genome and the environment, a percentage of cases is particularly due to …

A common feature of many cancers is that outcomes generally are more favorable when a
disease is detected at a localized stage, and treatment is initiated early in the disease's …