Serum levels of insulin-like growth factor I and its binding proteins in health and disease

A Juul - Growth hormone & IGF research, 2003 - Elsevier
Postnatal growth and development of the human body and its specific organs are regulated
by a complex network of local and systemic factors which is poorly understood. This review …

Growth hormone, IGF‐I and insulin and their abuse in sport

RIG Holt, PH Sönksen - British journal of pharmacology, 2008 - Wiley Online Library
There is widespread anecdotal evidence that growth hormone (GH) is used by athletes for
its anabolic and lipolytic properties. Although there is little evidence that GH improves …

The systemic effects of platelet-rich plasma injection

AS Wasterlain, HJ Braun, AHS Harris… - … American journal of …, 2013 - journals.sagepub.com
Background: Platelet-rich plasma (PRP) is an autologous blood product used to treat acute
and chronic tendon, ligament, and muscle injuries in over 86,000 athletes in the United …

The growth hormone/insulin-like growth factor-I axis in exercise and sport

J Gibney, ML Healy, PH Sönksen - Endocrine reviews, 2007 - academic.oup.com
The syndrome of adult GH deficiency and the effects of GH replacement therapy provide a
useful model with which to study the effects of the GH/IGF-I axis on exercise physiology …

Systematic review: the effects of growth hormone on athletic performance

H Liu, DM Bravata, I Olkin, A Friedlander… - Annals of internal …, 2008 - acpjournals.org
Background: Human growth hormone is reportedly used to enhance athletic performance,
although its safety and efficacy for this purpose are poorly understood. Purpose: To evaluate …

The effects of growth hormone on body composition and physical performance in recreational athletes: a randomized trial

U Meinhardt, AE Nelson, JL Hansen… - Annals of internal …, 2010 - acpjournals.org
Background: Growth hormone is widely abused by athletes, frequently with androgenic
steroids. Its effects on performance are unclear. Objective: To determine the effect of growth …

Use of growth hormone, IGF-I, and insulin for anabolic purpose: Pharmacological basis, methods of detection, and adverse effects

LJ Anderson, JM Tamayose, JM Garcia - Molecular and cellular …, 2018 - Elsevier
Hormones with anabolic properties such as growth hormone (GH), insulin-like growth factor-
1 (IGF-I), and insulin are commonly abused among professional and recreational athletes to …

Endocrine profiles in 693 elite athletes in the postcompetition setting

ML Healy, J Gibney, C Pentecost… - Clinical …, 2014 - Wiley Online Library
Objective To measure a profile of hormones in a group of elite athletes. Increasing
awareness of the widespread use of hormones as performance‐enhancing agents focusses …

IGF1 and IGFBP3 tagging polymorphisms are associated with circulating levels of IGF1, IGFBP3 and risk of breast cancer

A Al-Zahrani, MS Sandhu, RN Luben… - Human molecular …, 2006 - academic.oup.com
Experimental and observational studies in humans and animals suggest that insulin-like
growth factor 1 (IGF1) and its principal binding protein, IGFBP3, may influence breast cancer …

The use and abuse of growth hormone in sports

RIG Holt, KKY Ho - Endocrine reviews, 2019 - academic.oup.com
GH is banned by the World Anti-Doping Agency as a performance-enhancing anabolic
agent. Doping with GH likely began in the early 1980s and became more prevalent with the …