In neurological diseases, the actions of microglia, the resident myeloid cells of the CNS
parenchyma, may diverge from, or intersect with, those of recruited monocytes to drive …

Microglia are key players of the immune response in the central nervous system (CNS) and,
being the resident innate immune cells, they are responsible for the early control of …

PLX5622 is a CSF-1R inhibitor and microglia-depleting reagent, widely used to investigate
the biology of this central nervous system (CNS)-resident myeloid population, but the …

Viral encephalitis is still very prominent around the world, and traditional antiviral therapies
still have shortcomings. Some patients cannot get effective relief or suffer from serious …

Abstract The flaviviruses dengue, West Nile, and Japanese encephalitis represent three
major mosquito-borne viruses worldwide. These pathogens impact the lives of millions of …

Since 1999, there have been nearly 20,000 cases of confirmed symptomatic West Nile virus
(WNV) infection in the United States, and it is likely that more than 1 million people have …

M. Müller, S. Carter, MJ Hofer and IL Campbell (2010) Neuropathology and Applied
Neurobiology36, 368–387 The chemokine receptor CXCR3 and its ligands CXCL9 …

Neurological complications such as inflammation, failure of the blood-brain barrier (BBB),
and neuronal death contribute to the mortality and morbidity associated with WNV-induced …

At the end of 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was
discovered in China, causing a new coronavirus disease, termed COVID-19 by the WHO on …

This review describes the role of CXCL1, a chemokine crucial in inflammation as a
chemoattractant for neutrophils, in physiology and in selected major non-cancer diseases …