Ecto-nucleotidases play a pivotal role in purinergic signal transmission. They hydrolyze
extracellular nucleotides and thus can control their availability at purinergic P2 receptors …

ATP serves not only as an energy source for all cell types but as an 'extracellular messenger-
for autocrine and paracrine signalling. It is released from the cell via several different …

We show theoretically how adenosine 5′-triphosphate (ATP)-induced dynamic
dissociations of spectrin filaments (from each other and from the membrane) in the …

Dimethyl sulfoxide (DMSO) is widely used in a number of biological and biotechnological
applications, mainly because of its effects on the cell plasma membrane, but the molecular …

Platelets are well recognized as a key cell component of the hemostatic system. Recently,
several additional functions have been discovered for these blood cells but most importantly …

Cystic Fibrosis (CF) is a frequent and lethal autosomal recessive disease, caused by
mutations in the gene encoding the Cystic Fibrosis Transmembrane Conductance Regulator …

Cystic fibrosis (CF) is caused by a mutation of the gene encoding the cystic fibrosis
transmembrane conductance regulator (CFTR). We examined platelet function in CF …

Platelets are an important, albeit generally underappreciated, component of the
inflammatory cascade. Platelets are known to contribute to inflammation in atherosclerosis …

Cystic fibrosis (CF) is a genetic, multisystemic disorder with broad clinical manifestations
apart from the well-characterized pulmonary dysfunction. Recent findings have described …

During the past three decades, electrophysiological studies revealed that human red blood
cell membrane is endowed with a large variety of ion channels. The physiological role of …