While the processing of mRNA is essential for gene expression, recent findings have
highlighted that RNA processing is systematically altered in cancer. Mutations in RNA …

RNA molecules start assembling into ribonucleoprotein (RNP) complexes during
transcription. Dynamic RNP assembly, largely directed by cis-acting elements on the RNA …

Most human genes have multiple sites at which RNA 3ʹ end cleavage and polyadenylation
can occur, enabling the expression of distinct transcript isoforms under different conditions …

The chemical modification of RNA is a newly discovered epigenetic regulation mechanism
in cells and plays a crucial role in a variety of biological processes. N6-methyladenine (m6A) …

Generated by 3′ end cleavage and polyadenylation at alternative polyadenylation (poly
(A)) sites, alternative terminal exons account for much of the variation between human …

Glioblastoma (GBM) is a grade IV glioma that is the most malignant brain tumor type.
Currently, there are no effective and sufficient therapeutic strategies for its treatment …

Occurring in over 60% of human genes, alternative polyadenylation (APA) results in
numerous transcripts with differing 3'ends, thus greatly expanding the diversity of mRNAs …

Messanger RNA (mRNA) isoforms with alternative 3′‐untranslated regions (3′‐UTRs) are
produced by alternative polyadenylation (APA), which occurs during transcription in most …

The tremendous rate with which data is generated and analysis methods emerge makes it
increasingly difficult to keep track of their domain of applicability, assumptions, limitations …

Alternative polyadenylation (APA) yields transcripts differing in their 3′-end, and its
regulation is altered in cancer, including prostate cancer. Here we have uncovered a …