FMRFamides are evolutionarily conserved neuropeptides that play critical roles in behavior,
energy balance, and reproduction. Here, we show that FMRFamide signaling from the …

Proximity-dependent labeling approaches such as BioID have been a great boon to studies
of protein-protein interactions in the context of cytoskeletal structures such as centrosomes …

Transgenerational epigenetic inheritance (TEI) is mostly discussed in the context of
physiological or environmental factors. Here, we show intergenerational and …

Glutamate-gated chloride channels are the most important target of ivermectin and related
compounds in parasitic nematodes. A small family of genes encode subunits of these …

The Caenorhabditis elegans somatic gonadal precursors (SGPs) are multipotent progenitors
that generate all somatic cells of the adult reproductive system. The 2 SGPs originate in the …

Multipotent stem and progenitor cells have the capacity to generate a limited array of related
cell types. The Caenorhabditis elegans somatic gonadal precursors are multipotent …

Neuropeptides in the brain have both excitatory and inhibitory effects on neuronal activity
through paracrine signaling to local circuits. Here, we show that neuropeptides can activate …

Comprised of only 20 cells, the Caenorhabditis elegans intestine is the nexus of many life-
supporting functions, including digestion, metabolism, aging, immunity, and environmental …

The Caenorhabditis elegans somatic gonadal precursors (SGPs) are multipotent progenitors
that generate all somatic cells of the adult reproductive system. The two SGPs originate in …

The Wnt signaling pathway is a highly conserved cell signaling pathway that regulates cell
fate determination and maintains adult stem cell populations, and when misregulated …