E Barbieri, P Sestili - Journal of signal transduction, 2012 - Wiley Online Library
Generation of reactive oxygen species (ROS) is a ubiquitous phenomenon in eukaryotic cells′ life. Up to the 1990s of the past century, ROS have been solely considered as toxic …
EC Gomes, AN Silva, MR Oliveira - Oxidative medicine and …, 2012 - Wiley Online Library
This review offers an overview of the influence of reactive species produced during exercise and their effect on exercise adaptation. Reactive species and free radicals are unstable …
Sarcopenia, the loss of skeletal muscle mass and function that occurs with aging, is associated with increased risk for several adverse health outcomes, including frailty …
BM Scicchitano, L Pelosi, G Sica, A Musarò - Mechanisms of Ageing and …, 2018 - Elsevier
Muscle senescence is a complex mechanism that is usually associated with a decrease in mass, strength and velocity of contraction. This state, known as sarcopenia, is a multifactorial …
G Morris, M Berk, P Galecki, K Walder, M Maes - Molecular neurobiology, 2016 - Springer
Many patients with systemic immune-inflammatory and neuro-inflammatory disorders, including depression, rheumatoid arthritis, systemic lupus erythematosus, Sjögren's disease …
M uscle aging is characterized by a decline in functional performance and restriction of adaptability, due to progressive loss of muscle tissue coupled with a decrease in strength …
L Barberi, BM Scicchitano, M De Rossi, A Bigot… - Biogerontology, 2013 - Springer
Although adult skeletal muscle is composed of fully differentiated fibers, it retains the capacity to regenerate in response to injury and to modify its contractile and metabolic …
E Zilio, V Piano, B Wirth - International Journal of Molecular Sciences, 2022 - mdpi.com
Spinal muscular atrophy (SMA) is a devastating neuromuscular disorder caused by recessive mutations in the SMN1 gene, globally affecting~ 8–14 newborns per 100,000. The …
Sarcopenia is an age-related and accelerated process characterized by a progressive loss of muscle mass and strength/function. It is a multifactorial process associated with several …