Abstract Type 2 diabetes (T2DM) is a persistent metabolic disorder rising rapidly worldwide.
It is characterized by pancreatic insulin resistance and β-cell dysfunction. Hyperglycemia …

Diabetes mellitus is a group of metabolic disorders characterized by hyperglycemia caused
by resistance to insulin action, inadequate insulin secretion, or excessive glucagon …

Background Diabetic polyneuropathy (DPN) is the most common and early developing
complication of diabetes mellitus, and the key contributor for foot ulcers development, with …

Abstract Aldose reductase (AR, AKR1B1; EC 1.1. 1.21) is an aldo‐keto reductase that has
been widely investigated as an enzyme crucially involved in the pathogenesis of several …

Twenty benzothiazole derivatives bearing a 1, 3, 4-oxadiazole moiety were synthesized and
evaluated for their anti-oxidant and anti-inflammatory activities. Among these compounds …

Enhancing and protecting testosterone production is one target for many scientists because
of its crucial role as a primary sex hormone in males. Several in vivo trials have utilized …

Significance: Type 2 diabetes mellitus, which is related to oxidative stress and mitochondrial
dysfunction, is one of the most prevalent diseases in the world. In the past decade …

Diabetes remains a major health emergency in our entire world, affecting hundreds of
millions of people worldwide. In conjunction with its much-dreaded complications (eg …

Oxidative stress is an important factor in the development of type 2 diabetes (T2D) and
associated complications. Unfortunately, most clinical studies have failed to provide …

Numerous studies have implicated oxidative stress in the development of complications of
diabetes. During hyperglycemia, production of oxidant agents such as reactive oxygen …