Neural crest cells are a vertebrate-specific migratory, multipotent cell population that give
rise to a diverse array of cells and tissues during development. Cranial neural crest cells, in …

Phenotypic plasticity–the ability of an individual organism to alter its features in direct
response to a change in its environment–is ubiquitous. Understanding how and why this …

Canalization, or robustness to genetic or environmental perturbations, is fundamental to
complex organisms. While there is strong evidence for canalization as an evolved property …

Transcriptional regulation exhibits extensive robustness, but human genetics indicates
sensitivity to transcription factor (TF) dosage. Reconciling such observations requires …

Developmental systems integrate inputs of variation from different origins into the
observable variation of the resulting phenotype. Different components of phenotypic …

Domestic animals are ubiquitous. In contrast to the biodiversity crisis currently impacting
many kinds of animals and plants, not a single domesticated species is endangered …

With the growing amount and diversity of intermediate omics data complementary to
genomics (eg DNA methylation, gene expression, and protein abundance), there is a need …

The relationship between the evolutionary dynamics observed in contemporary populations
(microevolution) and evolution on timescales of millions of years (macroevolution) has been …

Although the evolutionary importance of adaptive phenotypic plasticity as a mechanism of
adaptation to spatial and temporal environmental variation is acknowledged as part of the …

The inhibitory cascade (IC) model is a widely used evolutionary developmental explanation
of among-species differences in relative molar tooth size. The IC model posits that, as …