Role of biomarker tests for diagnosis of neuroendocrine tumours

J Hofland, WT Zandee, WW de Herder - Nature Reviews Endocrinology, 2018 - nature.com
Neuroendocrine tumours (NETs) are neoplasms that arise from neuroendocrine cells.
Neuroendocrine cells and their tumours can secrete a wide range of amines and …

Molecular imaging of gastroenteropancreatic neuroendocrine tumors: current status and future directions

CM Deroose, E Hindié, E Kebebew… - Journal of Nuclear …, 2016 - Soc Nuclear Med
Through diagnostic imaging and peptide receptor radionuclide therapy, nuclear medicine
has earned a major role in gastroenteropancreatic neuroendocrine tumors (GEP NETs) …

CD8-targeted PET imaging of tumor-infiltrating T cells in patients with cancer: a phase I first-in-humans study of 89Zr-Df-IAB22M2C, a radiolabeled anti-CD8 minibody

MD Farwell, RF Gamache, H Babazada… - Journal of Nuclear …, 2022 - Soc Nuclear Med
There is a need for in vivo diagnostic imaging probes that can noninvasively measure tumor-
infiltrating CD8+ leukocytes. Such imaging probes could be used to predict early response …

Glucagon-like peptide-1 receptor PET/CT with 68Ga-NOTA-exendin-4 for detecting localized insulinoma: a prospective cohort study

Y Luo, Q Pan, S Yao, M Yu, W Wu, H Xue… - Journal of Nuclear …, 2016 - Soc Nuclear Med
Preoperative localization of insulinoma is a clinical dilemma. We aimed to investigate
whether glucagon-like peptide-1 receptor (GLP-1R) PET/CT with 68Ga-NOTA-MAL-cys40 …

Comparison of glucagon-like peptide-1 receptor (GLP-1R) PET/CT, SPECT/CT and 3T MRI for the localisation of occult insulinomas: evaluation of diagnostic accuracy …

K Antwi, M Fani, T Heye, G Nicolas… - European journal of …, 2018 - Springer
Purpose Benign insulinomas are the most prevalent cause of endogenous
hyperinsulinaemic hypoglycaemia (EHH) in adults, and because of their small size are …

Imaging of pancreatic neuroendocrine tumors: recent advances, current status, and controversies

L Lee, T Ito, RT Jensen - Expert review of anticancer therapy, 2018 - Taylor & Francis
Introduction: Recently, there have been a number of advances in imaging pancreatic
neuroendocrine tumors (panNETs), as well as other neuroendocrine tumors (NETs), which …

Hyperinsulinaemic hypoglycaemia in children and adults

P Shah, SA Rahman, H Demirbilek… - The Lancet Diabetes & …, 2017 - thelancet.com
Pancreatic β cells are functionally programmed to release insulin in response to changes in
plasma glucose concentration. Insulin secretion is precisely regulated so that, under normal …

[PDF][PDF] Insulinomas: from diagnosis to treatment. A review of the literature

D Giannis, D Moris, GS Karachaliou, DI Tsilimigras… - J BUON, 2020 - researchgate.net
Insulinoma is the most common pancreatic neuroendocrine tumor (NET). Insulinomas are
most commonly benign, welldifferentiated NETs, whereas malignant neoplasms account for …

The β cell in diabetes: integrating biomarkers with functional measures

SE Kahn, YC Chen, N Esser, AJ Taylor… - Endocrine …, 2021 - academic.oup.com
The pathogenesis of hyperglycemia observed in most forms of diabetes is intimately tied to
the islet β cell. Impairments in propeptide processing and secretory function, along with the …

Localization of hidden insulinomas with 68Ga-DOTA-exendin-4 PET/CT: a pilot study

K Antwi, M Fani, G Nicolas… - Journal of Nuclear …, 2015 - Soc Nuclear Med
111In-DOTA-exendin-4 SPECT/CT has been shown to be highly efficient in the detection of
insulinomas. We aimed at determining whether novel PET/CT imaging with [Nle14, Lys40 …