Neuromyelitis optica spectrum disorder (NMOSD) is a rare inflammatory CNS disease that
primarily manifests as relapsing episodes of severe optic neuritis and myelitis. Diagnosis of …

Neuromyelitis optica spectrum disorders (NMOSD) are autoantibody mediated chronic
inflammatory diseases. Serum antibodies (Abs) against the aquaporin-4 water channel lead …

Introduction Severe attacks of neuromyelitis optica spectrum disorder (NMO-SD) are
improved by plasma exchange (PLEX) given as an adjunctive therapy. Initial studies failed …

Acute optic neuritis is the most common optic neuropathy affecting young adults. Exciting
developments have occurred over the past decade in understanding of optic neuritis …

The understanding of neuromyelitis optica spectrum disorder (NMOSD) has evolved
substantially since its initial description over a century ago. The discovery in 2004 of a …

Neuromyelitis optica (NMO, Devic's syndrome), long considered a clinical variant of multiple
sclerosis, is now regarded as a distinct disease entity. Major progress has been made in the …

Sjogren's syndrome: An update on disease pathogenesis, clinical manifestations and treatment
Sjogren's syndrome: An update on disease pathogenesis, clinical manifestations and treatment …

Summary The term 'neuromyelitis optica'('Devic's syndrome', NMO) refers to a syndrome
characterized by optic neuritis and myelitis. In recent years, the condition has raised …

Neuromyelitis optica (NMO) is an autoimmune disease of the CNS that is characterized by
inflammatory demyelinating lesions in the spinal cord and optic nerve, potentially leading to …

Background Complement activation after binding of an IgG autoantibody to aquaporin 4
(AQP4) is thought to be a major determinant of CNS inflammation and astrocytic injury in …