The Hertzian theory in AFM nanoindentation experiments regarding biological samples: Overcoming limitations in data processing

SV Kontomaris, A Malamou, A Stylianou - Micron, 2022 - Elsevier
Abstract Atomic Force Microscopy (AFM) nanoindentation is a powerful tool for the
mechanical nano-characterization of biological samples. However, the range of Young's …

Recent advances in AFM-based biological characterization and applications at multiple levels

W Liang, H Shi, X Yang, J Wang, W Yang, H Zhang… - Soft Matter, 2020 - pubs.rsc.org
Atomic force microscopy (AFM) has found a wide range of bio-applications in the past few
decades due to its ability to measure biological samples in natural environments at a high …

Cantilever-based sensors for high speed atomic force microscopy

BO Alunda, YJ Lee - Sensors, 2020 - mdpi.com
This review critically summarizes the recent advances of the microcantilever-based force
sensors for atomic force microscope (AFM) applications. They are one the most common …

Application of atomic force microscopy in critical force and critical time extraction of 2D manipulation for gastric cancer tissue with different friction models

M Taheri - Nanoscale, 2022 - nanomeghyas.ir
In order to better understand and improve the treatment of cancer, the study of the structural
properties and mechanical properties of healthy cell tissues is of great importance …

Investigating the effects of quercetin fatty acid esters on apoptosis, mechanical properties, and expression of ERK in melanoma cell line (A375)

M Aghamohammadi, L Zolghadr, NS Nezhad… - Life Sciences, 2022 - Elsevier
Aims Malignant melanoma (MM) is the most fatal skin cancer with a critical increase in the
number of cases in the last decades. Recent studies have shown the antitumor potential of …

Tissue mechanics modulate PCNP expression in oral squamous cell carcinomas with different differentiation

L Zhang, D Guo, J Shen, Y Zheng, J Zhai, R Li… - Frontiers in …, 2023 - frontiersin.org
Background PEST-containing nuclear protein (PCNP), a novel zinc finger protein,
participates in cell cycle regulation. Previous studies have confirmed that PCNP plays a role …

Novel scopoletin derivatives kill cancer cells by inducing mitochondrial depolarization and apoptosis

Z Shi, L Chen, J Sun - Anti-Cancer Agents in Medicinal …, 2021 - ingentaconnect.com
Background: Natural products and their molecular frameworks have been explored as
invaluable sources of inspiration for drug design by means of structural modification …

A lesson from earthquake engineering for selectively damaging cancer cell structures

M Fraldi, A Cutolo, AR Carotenuto, S Palumbo… - Journal of the …, 2021 - Elsevier
The progressive falling of barriers among disciplines is opening unforeseen scenarios in
diagnosis and treatment of cancer diseases. By sharing models and mature knowledge in …

Biomechanical imaging biomarker during chemoradiotherapy predicts treatment response in head and neck squamous cell carcinoma

K Fujimoto, T Shiinoki, Y Kawazoe… - Physics in Medicine …, 2024 - iopscience.iop.org
Objective. For response-adapted adaptive radiotherapy (R-ART), promising biomarkers are
needed to predict post-radiotherapy (post-RT) responses using routine clinical information …

Nanomechanical‐based classification of prostate tumor using atomic force microscopy

J Zeng, Y Zhang, R Xu, H Chen, X Tang, S Zhang… - The …, 2023 - Wiley Online Library
Background The loss of mechanical homeostasis between tumor cells and
microenvironment is an important factor in tumor metastasis. In the process, mechanical …