Role of oxidative stress in the pathogenesis of non-alcoholic fatty liver disease: Implications for prevention and therapy

JC Arroyave-Ospina, Z Wu, Y Geng, H Moshage - Antioxidants, 2021 - mdpi.com
Oxidative stress (OxS) is considered a major factor in the pathophysiology of inflammatory
chronic liver diseases, including non-alcoholic liver disease (NAFLD). Chronic impairment of …

Fructose and NAFLD: the multifaceted aspects of fructose metabolism

P Jegatheesan, JP De Bandt - Nutrients, 2017 - mdpi.com
Among various factors, such as an unhealthy diet or a sedentarity lifestyle, excessive
fructose consumption is known to favor nonalcoholic fatty liver disease (NAFLD), as fructose …

[HTML][HTML] Therapeutic effect of Sirtuin 3 on ameliorating nonalcoholic fatty liver disease: the role of the ERK-CREB pathway and Bnip3-mediated mitophagy

R Li, T Xin, D Li, C Wang, H Zhu, H Zhou - Redox Biology, 2018 - Elsevier
Increased mitochondrial damage is related to the progression of a diet-induced nonalcoholic
fatty liver disease. The aim of our study is to investigate the role of Sirtuin 3 (Sirt3) in treating …

Redox signaling and advanced glycation endproducts (AGEs) in diet-related diseases

V Cepas, M Collino, JC Mayo, RM Sainz - Antioxidants, 2020 - mdpi.com
Diets are currently characterized by elevated sugar intake, mainly due to the increased
consumption of processed sweetened foods and drinks during the last 40 years. Diet is the …

Theabrownin and Poria cocos Polysaccharide Improve Lipid Metabolism via Modulation of Bile Acid and Fatty Acid Metabolism

J Wang, D Zheng, F Huang, A Zhao, J Kuang… - Frontiers in …, 2022 - frontiersin.org
Nonalcoholic fatty liver disease (NAFLD) is prevalent worldwide, while no pharmaceutical
treatment has been approved. Natural herbs are promising for their amelioration effect on …

Nobiletin ameliorates nonalcoholic fatty liver disease by regulating gut microbiota and myristoleic acid metabolism

SZ Li, NN Zhang, X Yang, TQ Huang… - Journal of Agricultural …, 2023 - ACS Publications
Disturbance of the gut microbiota plays a critical role in the development of nonalcoholic
fatty liver disease (NAFLD). Increasing evidence supports that natural products may serve as …

Progress in nonalcoholic fatty liver disease: SIRT family regulates mitochondrial biogenesis

C Zeng, M Chen - Biomolecules, 2022 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) is characterized by hepatic steatosis, insulin
resistance, mitochondrial dysfunction, inflammation, and oxidative stress. As a group of …

The role of fructose in non-alcoholic steatohepatitis: old relationship and new insights

A Federico, V Rosato, M Masarone, P Torre, M Dallio… - Nutrients, 2021 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) represents the result of hepatic fat overload not
due to alcohol consumption and potentially evolving to advanced fibrosis, cirrhosis, and …

[HTML][HTML] Curcumin and other dietary polyphenols: Potential mechanisms of metabolic actions and therapy for diabetes and obesity

T Jin, Z Song, J Weng… - American Journal of …, 2018 - journals.physiology.org
Recent controversy regarding the therapeutic potential of curcumin indicates the challenges
to research in this field. Here, we highlight the investigations of curcumin and other plant …

The Protective Effects of p-Coumaric Acid on Acute Liver and Kidney Damages Induced by Cisplatin

FN Ekinci Akdemir, M Albayrak, M Çalik, Y Bayir… - Biomedicines, 2017 - mdpi.com
In this study, we aimed to investigate the effects of p-Coumaric acid (PCA) on cisplatin (CIS)-
induced hepatotoxicity and nephrotoxicity in Wistar adult rats for 24 h compared to untreated …