Controlling cell behavior electrically: current views and future potential

CD McCaig, AM Rajnicek, B Song… - Physiological …, 2005 - journals.physiology.org
Direct-current (DC) electric fields are present in all developing and regenerating animal
tissues, yet their existence and potential impact on tissue repair and development are …

[HTML][HTML] Bioelectric signaling in regeneration: mechanisms of ionic controls of growth and form

KA McLaughlin, M Levin - Developmental biology, 2018 - Elsevier
The ability to control pattern formation is critical for the both the embryonic development of
complex structures as well as for the regeneration/repair of damaged or missing tissues and …

The biofield hypothesis: Its biophysical basis and role in medicine

B Rubik - The Journal of Alternative & Complementary Medicine, 2002 - liebertpub.com
This paper provides a scientific foundation for the biofield: the complex, extremely weak
electromagnetic field of the organism hypothesized to involve electromagnetic …

Comparative aspects of animal regeneration

JP Brockes, A Kumar - Annual review of cell and developmental …, 2008 - annualreviews.org
Most but not all phyla include examples of species that are able to regenerate large sections
of the body plan. The mechanisms underlying regeneration on this scale are currently being …

Molecular bioelectricity in developmental biology: new tools and recent discoveries: control of cell behavior and pattern formation by transmembrane potential …

M Levin - Bioessays, 2012 - Wiley Online Library
Significant progress in the molecular investigation of endogenous bioelectric signals during
pattern formation in growing tissues has been enabled by recently developed techniques …

Application of direct current electric fields to cells and tissues in vitro and modulation of wound electric field in vivo

B Song, Y Gu, J Pu, B Reid, Z Zhao, M Zhao - Nature protocols, 2007 - nature.com
It has long been known that cells can be induced to migrate by the application of small dc
electric fields (EFs), a phenomenon referred to as galvanotaxis. We recently reported some …

Large-scale biophysics: ion flows and regeneration

M Levin - Trends in cell biology, 2007 - cell.com
Regeneration requires exquisite orchestration of growth and morphogenesis. A powerful but
still largely mysterious system of biophysical signals functions during regeneration …

H+ pump-dependent changes in membrane voltage are an early mechanism necessary and sufficient to induce Xenopus tail regeneration

DS Adams, A Masi, M Levin - 2007 - journals.biologists.com
In many systems, ion flows and long-term endogenous voltage gradients regulate patterning
events, but molecular details remain mysterious. To establish a mechanistic link between …

Membrane potential controls adipogenic and osteogenic differentiation of mesenchymal stem cells

S Sundelacruz, M Levin, DL Kaplan - PloS one, 2008 - journals.plos.org
Background Control of stem cell behavior is a crucial aspect of developmental biology and
regenerative medicine. While the functional role of electrophysiology in stem cell biology is …

Mechanisms of urodele limb regeneration

DL Stocum - Regeneration, 2017 - Wiley Online Library
This review explores the historical and current state of our knowledge about urodele limb
regeneration. Topics discussed are (1) blastema formation by the proteolytic histolysis of …