[HTML][HTML] Immune checkpoint blockade reprograms systemic immune landscape and tumor microenvironment in obesity-associated breast cancer
Immune checkpoint blockade (ICB) has improved outcomes in some cancers. A major
limitation of ICB is that most patients fail to respond, which is partly attributable to …
limitation of ICB is that most patients fail to respond, which is partly attributable to …
[HTML][HTML] Evaluating large language model (LLM) performance on established breast classification systems
Medical researchers are increasingly utilizing advanced LLMs like ChatGPT-4 and Gemini
to enhance diagnostic processes in the medical field. This research focuses on their ability …
to enhance diagnostic processes in the medical field. This research focuses on their ability …
[HTML][HTML] Cyclin A2 and Ki-67 proliferation markers could be used to identify tumors with poor prognosis in African American women with breast cancer
D Beyene, T Naab, V Apprey, L Ricks-Santi… - Journal of cancer …, 2023 - ncbi.nlm.nih.gov
Background: Diagnosed invasive breast carcinomas in African American patients are more
aggressive compared with those in Caucasian patients and diagnosed at later stages of the …
aggressive compared with those in Caucasian patients and diagnosed at later stages of the …
Investigation of the adolescent female breast transcriptome and the impact of obesity
A Burkholder, D Akrobetu, AR Pandiri, K Ton… - Breast Cancer …, 2020 - Springer
Background Early life environmental exposures affect breast development and breast
cancer risk in adulthood. The breast is particularly vulnerable during puberty when …
cancer risk in adulthood. The breast is particularly vulnerable during puberty when …
Immune-and metabolism-associated molecular classification of ovarian cancer
Z Chen, W Jiang, Z Li, Y Zong, G Deng - Frontiers in Oncology, 2022 - frontiersin.org
Ovarian cancer (OV) is a complex gynecological disease, and its molecular characteristics
are not clear. In this study, the molecular characteristics of OV subtypes based on metabolic …
are not clear. In this study, the molecular characteristics of OV subtypes based on metabolic …
NOTCH expression variability and relapse of breast cancer in high-risk groups
JD Gómez-Archila, AM Espinosa-García… - The American Journal of …, 2022 - Elsevier
Background In regards to breast cancer (BC), survival or disease-free periods are still
compromised mainly in Triple Negative (TN) and HER2 tumors. The participation of estrogen …
compromised mainly in Triple Negative (TN) and HER2 tumors. The participation of estrogen …
Comprehensive analysis of location-specific hub genes related to the pathogenesis of colon cancer
C Shi, K Ding, K Li, L Long, J Li, B Hu - Medical Oncology, 2020 - Springer
The molecular mechanisms underlying colon cancer lesions at different sites are not entirely
clear. Herein, we aimed to explore location-specific gene profiles related to the …
clear. Herein, we aimed to explore location-specific gene profiles related to the …
Gene-Level Germline Investigation of Breast Cancer Subtypes and Mortality Among Women of European and African Ancestry
AP Patel - 2022 - search.proquest.com
Genome-wide investigations to date have uncovered over 210 germline variants associated
with BC incidence, and only a handful of mostly non-replicable variants associated with BC …
with BC incidence, and only a handful of mostly non-replicable variants associated with BC …
Associations of breast cancer related exposures and gene expression profiles in normal breast tissue—The Norwegian Women and Cancer normal breast tissue study
S Krum‐Hansen, K Standahl Olsen… - Cancer …, 2023 - Wiley Online Library
Background Normal breast tissue is utilized in tissue‐based studies of breast
carcinogenesis. While gene expression in breast tumor tissue is well explored, our …
carcinogenesis. While gene expression in breast tumor tissue is well explored, our …