B Moukengue, M Lallier, L Marchandet, M Baud'huin… - Cancers, 2022 - mdpi.com
Simple Summary Osteosarcoma is the most common malignant bone tumor in children, with a 5-year survival rate ranging from 70% to 20% depending on the aggressiveness of the …
L Marchandet, M Lallier, C Charrier, M Baud'huin… - Cancers, 2021 - mdpi.com
Simple Summary Osteosarcoma (OS), the most common primary bone tumor, mainly affects children and adolescents. Unfortunately, in some cases, the absence of response to …
Bioceramics, such as calcium phosphate ceramics and cements and silica-based glasses, are widely used as components of implants for bone and teeth restoration. Nowadays, the …
K Ando, MF Heymann, V Stresing, K Mori, F Rédini… - Cancers, 2013 - mdpi.com
Osteosarcoma is the most frequent malignant primary bone tumor and a main cause of cancer-related death in children and adolescents. Although long-term survival in localized …
X Qi, Y Li, Y Zhang, T Xu, B Lu, L Fang, J Gao… - Acta Pharmacologica …, 2019 - nature.com
Despite more effective chemotherapy combined with limb-salvage surgery for the osteosarcoma treatment, survival rates for osteosarcoma patients have stagnated over the …
CE Macsai, BK Foster, CJ Xian - Journal of cellular physiology, 2008 - Wiley Online Library
Wnt signalling has an essential role in regulating bone formation and remodelling during embryonic development and throughout postnatal and adult life. Specifically, Wnt signalling …
Cancer cells maintain high levels of reactive oxygen species (ROS) to drive their growth, but ROS can trigger cell death through oxidative stress and DNA damage. To survive enhanced …
A Sakamoto, Y Iwamoto - Reviews on recent clinical trials, 2008 - ingentaconnect.com
Osteosarcoma is the most common primary bone tumor in childhood and adolescence. The use of combination chemotherapy and surgery enables long-term survival in approximately …
Z Gong, P Shen, H Wang, J Zhu, K Liang… - Aging (Albany …, 2023 - ncbi.nlm.nih.gov
Circular RNAs (circRNAs) have been demonstrated to have critical regulatory roles in tumorigenesis. However, the contribution of circRNAs to OS (osteosarcoma) remains largely …