Cancer drug resistance is an enormous problem. It is responsible for most relapses in
cancer patients following apparent remission after successful therapy. Understanding …

Ovarian cancer is a disease with a poor prognosis and little progress has been made to
improve treatment. It is now recognized that there are several histotypes of ovarian cancer …

Malignant ovarian tumors bear the highest mortality rate among all gynecological cancers.
Both late tumor diagnosis and tolerance to available chemical therapy increase patient …

The majority of women diagnosed with epithelial ovarian cancer eventually develop
recurrence, which rapidly evolves into chemoresistant disease. Persistence of ovarian …

Any alteration at the genetic or epigenetic level, may result in multiplex of diseases including
tumorigenesis which ultimately results in the cancer development. Restoration of the normal …

Ovarian cancer (OC) is a heterogeneous disease usually diagnosed at a late stage. Cancer
stem cells (CSCs) that exist within the bulk tumor survive first-line chemotherapy and …

Overexpression of HDAC 2 promotes cell proliferation in ovarian cancer. HDAC 2 is involved
in chromatin remodeling, transcriptional repression, and the formation of condensed …

Background Ovarian cancer (OvCa) is the leading cause of death of gynecological
malignancies worldwide. Vascular endothelial growth factor A (VEGFA), the most potent …

Breast cancer persists as the most common cause of cancer death in women worldwide.
Ovarian cancer is also a significant source of morbidity and mortality, as the fifth leading …

Background/Aims: Cisplatin-based treatment is first-line chemotherapy for several cancers
including ovarian cancer. The development of cisplatin resistance results in treatment …