Architecture, function, and substrates of the type II secretion system
KV Korotkov, M Sandkvist - EcoSal Plus, 2019 - Am Soc Microbiol
The type II secretion system (T2SS) delivers toxins and a range of hydrolytic enzymes,
including proteases, lipases, and carbohydrate-active enzymes, to the cell surface or …
including proteases, lipases, and carbohydrate-active enzymes, to the cell surface or …
Interplay between peptidoglycan biology and virulence in Gram-negative pathogens
The clinical and epidemiological threat of the growing antimicrobial resistance in Gram-
negative pathogens, particularly for β-lactams, the most frequently used and relevant …
negative pathogens, particularly for β-lactams, the most frequently used and relevant …
Peptidoglycan remodeling enables Escherichia coli to survive severe outer membrane assembly defect
Gram-negative bacteria have a tripartite cell envelope with the cytoplasmic membrane (CM),
a stress-bearing peptidoglycan (PG) layer, and the asymmetric outer membrane (OM) …
a stress-bearing peptidoglycan (PG) layer, and the asymmetric outer membrane (OM) …
The trans‐envelope architecture and function of the type 2 secretion system: New insights raising new questions
JL Thomassin, J Santos Moreno, I Guilvout… - Molecular …, 2017 - Wiley Online Library
Nanomachines belonging to the type IV filament (Tff) superfamily serve a variety of cellular
functions in prokaryotes, including motility, adhesion, electrical conductance, competence …
functions in prokaryotes, including motility, adhesion, electrical conductance, competence …
[PDF][PDF] Peptidoglycan remodeling enables Escherichia coli to survive severe outer membrane assembly defect. mBio 10: e02729-18
Gram-negative bacteria have a tripartite cell envelope with the cytoplasmic membrane (CM),
a stress-bearing peptidoglycan (PG) layer, and the asymmetric outer membrane (OM) …
a stress-bearing peptidoglycan (PG) layer, and the asymmetric outer membrane (OM) …
A comprehensive understanding of the influence and molecular mechanism of exeA on the pathogenicity in Aeromonas hydrophila
C Xiong, H Jiao, J Ran, D Li, Z Li, B Wang… - International Journal of …, 2025 - Elsevier
Aeromonas hydrophila is a serious human and animal co-pathogenic bacterium. The type II
secretion system (T2SS), a key virulence factor, is vital for the secretion of exotoxins from the …
secretion system (T2SS), a key virulence factor, is vital for the secretion of exotoxins from the …
Genome-wide analysis in Escherichia coli unravels a high level of genetic homoplasy associated with cefotaxime resistance
JPM Coolen, EPM den Drijver… - Microbial …, 2021 - microbiologyresearch.org
Cefotaxime (CTX) is a third-generation cephalosporin (3GC) commonly used to treat
infections caused by Escherichia coli. Two genetic mechanisms have been associated with …
infections caused by Escherichia coli. Two genetic mechanisms have been associated with …
Scaffolding protein GspB/OutB facilitates assembly of the Dickeya dadantii type 2 secretion system by anchoring the outer membrane secretin pore to the inner …
S Zhang, S Gu, P Rycroft, F Ruaudel, F Delolme… - Mbio, 2022 - Am Soc Microbiol
The phytopathogenic proteobacterium Dickeya dadantii secretes an array of plant cell wall-
degrading enzymes and other virulence factors via the type 2 secretion system (T2SS) …
degrading enzymes and other virulence factors via the type 2 secretion system (T2SS) …
In situ structures of secretins from bacterial type II secretion system reveal their membrane interactions and translocation process
The GspD secretin is the outer membrane channel of the bacterial type II secretion system
(T2SS) which secrets diverse effector proteins or toxins that cause severe diseases such as …
(T2SS) which secrets diverse effector proteins or toxins that cause severe diseases such as …
Membrane translocation process revealed by in situ structures of type II secretion system secretins
The GspD secretin is the outer membrane channel of the bacterial type II secretion system
(T2SS) which secrets diverse toxins that cause severe diseases such as diarrhea and …
(T2SS) which secrets diverse toxins that cause severe diseases such as diarrhea and …