Translational control and the cancer cell response to stress
N Robichaud, N Sonenberg - Current opinion in cell biology, 2017 - Elsevier
The evidence for the importance of aberrant translation in cancer cells is overwhelming.
Reflecting the wealth of data, there are excellent reviews delineating how ribosomes and …
Reflecting the wealth of data, there are excellent reviews delineating how ribosomes and …
Synthesis and evaluation of 2′ H-spiro [cyclohexane-1, 3′-imidazo [1, 5-a] pyridine]-1′, 5′-dione derivatives as Mnk inhibitors
AM Abdelaziz, SKC Basnet, S Islam, M Li… - Bioorganic & Medicinal …, 2019 - Elsevier
Post-translational modulation of eIF4E through phosphorylation by Mnks is highly integral to
the pathogenesis of different cancers. Therefore, inhibition of Mnks offers a strategy for …
the pathogenesis of different cancers. Therefore, inhibition of Mnks offers a strategy for …
Role of RONS and eIFs in Cancer Progression
YA Salaheldin, SSM Mahmoud… - Oxidative Medicine …, 2021 - Wiley Online Library
Various research works have piled up conflicting evidence questioning the effect of oxidative
stress in cancer. Reactive oxygen and nitrogen species (RONS) are the reactive radicals …
stress in cancer. Reactive oxygen and nitrogen species (RONS) are the reactive radicals …
[PDF][PDF] A walk through the process of translation: eIF4E in resected surgical margins in oral squamous cell carcinoma
MMS Dhume - Indian Journal of Pathology and Oncology, 2023 - academia.edu
Head and neck squamous cell carcinoma (HNSCC) represent includes cancers of the oral
cavity, larynx, and oropharynx. In relation to Oral squamous cell carcinoma (OSCC), a panel …
cavity, larynx, and oropharynx. In relation to Oral squamous cell carcinoma (OSCC), a panel …
Investigation of cap-independent translation in neuronal differentiation
L Ruhe - 2020 - edoc.hu-berlin.de
Translation initiation is a complex and highly regulated process which involves the assembly
of an elongation competent ribosome on the mRNA. The vast majority of eukaryotic mRNAs …
of an elongation competent ribosome on the mRNA. The vast majority of eukaryotic mRNAs …
Inhibition of eIF4F complex loading inhibits the survival of malignant glioma
QF Dong, ZF Yan, PQ Li, X Yang… - Oncology …, 2018 - spandidos-publications.com
The eukaryotic initiation factor (eIF) 4E-binding proteins (4E-BPs) regulate cap-dependent
protein translation and control the assembly of the eIF4F complex. In the present study, a …
protein translation and control the assembly of the eIF4F complex. In the present study, a …
[图书][B] Metastasis and the Impact of Translation in the Tumor and Host: a phospho-eIF4E Story
N Robichaud - 2017 - search.proquest.com
Most cancer related deaths are due to metastatic progression. While deregulated protein
synthesis in cancer cells is recognized as playing a major role in tumorigenesis, the …
synthesis in cancer cells is recognized as playing a major role in tumorigenesis, the …